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Dosing Recommendations for Concomitant Medications During 3D Anti-HCV TherapyExamination of 209 drugs for inhibition of cytochrome P450 2C8Summary of information on human CYP enzymes: human P450 metabolism data.Metabolizing enzyme toxicology assay chip (MetaChip) for high-throughput microscale toxicity analyses.Human liver expression of CYP2C8: gender, age, and genotype effects.Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifeneEffects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases.Sucralose, a synthetic organochlorine sweetener: overview of biological issuesRole of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries.The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjectsCoadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide.Pharmacology, pharmacokinetics and pharmacogenomics of paclitaxel.Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria.Rosiglitazone Metabolism in Human Liver Microsomes Using a Substrate Depletion Method.Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity.In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability.PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8.Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models.Effect of multiple doses of montelukast on the pharmacokinetics of rosiglitazone, a CYP2C8 substrate, in humansCYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide.Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects.Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates.Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
The xenobiotic inhibitor profile of cytochrome P4502C8.
@ast
The xenobiotic inhibitor profile of cytochrome P4502C8.
@en
type
label
The xenobiotic inhibitor profile of cytochrome P4502C8.
@ast
The xenobiotic inhibitor profile of cytochrome P4502C8.
@en
prefLabel
The xenobiotic inhibitor profile of cytochrome P4502C8.
@ast
The xenobiotic inhibitor profile of cytochrome P4502C8.
@en
P2093
P2860
P1476
The xenobiotic inhibitor profile of cytochrome P4502C8.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2125.2000.00316.X
P407
P577
2000-12-01T00:00:00Z