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Ethanol opens G-protein-activated inwardly rectifying K+ channels

Ethanol opens G-protein-activated inwardly rectifying K+ channels

http://www.wikidata.org/entity/Q28376797

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The mechanistic classification of addictive drugs Association between KCNJ6 (GIRK2) gene polymorphisms and postoperative analgesic requirements after major abdominal surgery Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior Neuropharmacology of alcohol addiction Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513 Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine A discrete alcohol pocket involved in GIRK channel activation Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells Behavioral and Genetic Evidence for GIRK Channels in the CNS: Role in Physiology, Pathophysiology, and Drug Addiction Advances in Electrophysiological Research Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disorders Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs.Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels Synaptic effects induced by alcohol.Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol.Possible involvement of Fyn kinase in ethanol-stimulated Cas tyrosine phosphorylation in rat cerebellum and cerebral cortex.Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3.Low dose acute alcohol effects on GABA A receptor subtypes Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity.Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis.Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil.Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants.Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain.Update on the neurobiology of alcohol withdrawal seizures.Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid.Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans.Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers A pervasive mechanism for analgesia: activation of GIRK2 channels.Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line.Functional characterization of an endogenous Xenopus oocyte adenosine receptor.Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q.The Selective Serotonin Reuptake Inhibitor Paroxetine, but not Fluvoxamine, Decreases Methamphetamine Conditioned Place Preference in Mice.GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol.A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: a commentary.Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors as an opportunity for drug development?

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P2860

Ethanol opens G-protein-activated inwardly rectifying K+ channels

http://www.wikidata.org/entity/Q28376797

description

1999 nî lūn-bûn

@nan

1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

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1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

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1999年论文

@wuu

name

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@ast

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@en

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@nl

type

label

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@ast

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@en

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@nl

prefLabel

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@ast

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@en

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@nl

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Nature Neuroscience

P1476

Ethanol opens G-protein-activated inwardly rectifying K+ channels

@en

P2093

H Kojima

http://www.w3.org/2001/XMLSchema#string

H Niki

http://www.w3.org/2001/XMLSchema#string

K Ikeda

http://www.w3.org/2001/XMLSchema#string

R Yano

http://www.w3.org/2001/XMLSchema#string

T Kobayashi

http://www.w3.org/2001/XMLSchema#string

T Kumanishi

http://www.w3.org/2001/XMLSchema#string

T Yoshioka

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P2860

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins

Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain

Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel

Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

Effects of ethanol on calcium channels, potassium channels, and vasopressin release.

Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication.

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1091-7

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scholarly article

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10.1038/16019

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12

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2

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1999-12-01T00:00:00Z

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12729726

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1015041697

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10570486

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