Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
about
Alcoholism: A Systems Approach From Molecular Physiology to Addictive BehaviorNeuropharmacology of alcohol addictionHow drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionStructural basis for the inhibition of firefly luciferase by a general anesthetic.Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia.Low-dose alcohol actions on alpha4beta3delta GABAA receptors are reversed by the behavioral alcohol antagonist Ro15-4513Ethanol potently and competitively inhibits binding of the alcohol antagonist Ro15-4513 to alpha4/6beta3delta GABAA receptorsGeneral anaesthetic actions on ligand-gated ion channelsGABA A receptors: subtypes provide diversity of function and pharmacologyInternational Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. UpdateA discrete alcohol pocket involved in GIRK channel activationFour-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analysesAnesthetic modulation of protein dynamics: insight from an NMR studyMolecular targets underlying general anaesthesiaCharacterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic propertiesChannel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segmentMutational analysis of molecular requirements for the actions of general anaesthetics at the gamma-aminobutyric acidA receptor subtype, alpha1beta2gamma2Multiple synaptic and membrane sites of anesthetic action in the CA1 region of rat hippocampal slicesPotentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?General anesthesia mediated by effects on ion channelsThe molecular pharmacology of volatile anestheticsState-dependent and reflex drives to the upper airway: basic physiology with clinical implicationsTop-down mechanisms of anesthetic-induced unconsciousnessP2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disordersStructure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogasterThe Role of Multiple Hydrogen-Bonding Groups in Specific Alcohol Binding Sites in Proteins: Insights from Structural Studies of LUSHMultisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channelA locally closed conformation of a bacterial pentameric proton-gated ion channelOpen-channel structures of the human glycine receptor α1 full-length transmembrane domain.Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol.Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndromeThe actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutationsTwo gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptorsMethionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anestheticsGoalpha regulates volatile anesthetic action in Caenorhabditis elegansSelective blocking effects of tropisetron and atropine on recombinant glycine receptorsGeneral anesthetic action at an internal protein site involving the S4-S5 cytoplasmic loop of a neuronal K(+) channelEthanol opens G-protein-activated inwardly rectifying K+ channelsMolecular sites for the positive allosteric modulation of glycine receptors by endocannabinoids
P2860
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P2860
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Sites of alcohol and volatile anaesthetic action on GABA
@nl
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@ast
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@en
type
label
Sites of alcohol and volatile anaesthetic action on GABA
@nl
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@ast
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@en
prefLabel
Sites of alcohol and volatile anaesthetic action on GABA
@nl
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@ast
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.
@en
P2093
P356
P1433
P1476
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
@en
P2093
Greenblatt EP
Harrison NL
Koltchine VV
Valenzuela CF
P2888
P304
P356
10.1038/38738
P407
P577
1997-09-01T00:00:00Z
P5875
P6179
1046182764