BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
about
Salivary PYY: a putative bypass to satietyNeuropeptide Y and EpilepsyNeuropeptides and their receptors: innovative science providing novel therapeutic targetsFunctional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissuesNeuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosaCentral neuropeptide Y receptors are involved in 3rd ventricular ghrelin induced alteration of colonic transit time in conscious fed ratsVascular pharmacology of BIIE0246, the first selective non-peptide neuropeptide Y Y(2) receptor antagonist, in vivoEffects of a selective neuropeptide Y Y2 receptor antagonist, BIIE0246, on Y2 receptors at peripheral neuroeffector junctionsPhysiological role of neuropeptide Y in the regulation of the ascending phase of the peristaltic reflexBlockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246Effect of pharmacological manipulations of neuropeptide Y and corticotropin-releasing factor neurotransmission on incubation of conditioned fearThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsChicken neuropeptide Y receptor Y2: structural and pharmacological differences to mammalian Y2(1).Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screeningPeripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious miceIntravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour.The neuropeptide y y(1) receptor: a diagnostic marker? Expression in mcf-7 breast cancer cells is down-regulated by antiestrogens in vitro and in xenografts.Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion.BIIE0246, a potent and highly selective non-peptide neuropeptide Y Y(2) receptor antagonistGalanin and neuropeptide Y reduce cholinergic transmission in the heart of the anaesthetised mouseThe ability of neuropeptide Y to mediate responses in the murine cutaneous microvasculature: an analysis of the contribution of Y1 and Y2 receptors.Pharmacological analysis of functional neurovascular transmission in canine splenic arteries: role of neuropeptide Y.NPY receptors as potential targets for anti-obesity drug development.Endogenous neuropeptide Y depresses the afferent signaling of gastric acid challenge to the mouse brainstem via neuropeptide Y type Y2 and Y4 receptors.Endogenous peptide YY and neuropeptide Y inhibit colonic ion transport, contractility and transit differentially via Y₁ and Y₂ receptorsOligomerization of neuropeptide Y (NPY) Y2 receptors in CHO cells depends on functional pertussis toxin-sensitive G-proteins.The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptorsNeuropeptide Y2 receptors are involved in enhanced neurogenic vasoconstriction in spontaneously hypertensive ratsCentral neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptorsSynthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonistsTherapeutic potential of neuropeptide Y (NPY) receptor ligands.Peptide YY3-36 decreases reinstatement of high-fat food seeking during dieting in a rat relapse model.Ligands of the neuropeptide Y Y2 receptor.Neuropeptide Y: potential role in recurrent developmental seizures.Stress-induced changes in adrenal neuropeptide Y expression are regulated by a negative feedback loop.Neuropeptide y gates a stress-induced, long-lasting plasticity in the sympathetic nervous system.Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms.Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance.Salivary peptide tyrosine-tyrosine 3-36 modulates ingestive behavior without inducing taste aversion.Neuropeptide Y and neurovascular control in skeletal muscle and skin
P2860
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P2860
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@ast
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@en
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@nl
type
label
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@ast
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@en
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@nl
prefLabel
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@ast
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@en
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@nl
P2093
P1476
BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist
@en
P2093
G Schnorrenberg
H A Wieland
H Dollinger
W Eberlein
P356
10.1016/S0014-2999(99)00650-0
P407
P577
1999-11-19T00:00:00Z