Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages
about
Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stressNew synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride. A novel and highly potent anti-inflammatory and cytoprotective agent.Proteomic analysis shows synthetic oleanane triterpenoid binds to mTORMetabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivativesTricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agentsDesign, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring AUnifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs.Structure-dependent inhibition of bladder and pancreatic cancer cell growth by 2-substituted glycyrrhetinic and ursolic acid derivatives.Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: highly potent anti-inflammatory and cytoprotective agents.Keap1 eye on the target: chemoprevention of liver cancer.Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cellsInduction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative.Oleanane derivatives for pharmaceutical use: a patent review (2000-2016).Semisynthetic ursolic acid fluorolactone derivatives inhibit growth with induction of p21(waf1) and induce apoptosis with upregulation of NOXA and downregulation of c-FLIP in cancer cells.Synthesis and biological evaluation of oleanolic acid derivatives as antitumor agents.Synthetic triterpenoid CDDO derivatives modulate cytoprotective or immunological properties in astrocytes, neurons, and microglia.CDDO and ATRA Instigate Differentiation of IMR32 Human Neuroblastoma Cells.Chemical modifications of natural triterpenes - glycyrrhetinic and boswellic acids: evaluation of their biological activity.Recent advances in synthesis and biological activity of triterpenic acylated oximes.AN EFFICIENT SYNTHESIS OF TRICYCLIC COMPOUNDS, (+/-)-(4abeta8abeta10aalpha)-1,2,3,4,4a,6,7,8,8a,9,10,10a-DODECAHYDRO-1,1,4a-TRIMETHYL-2-OXOPHENANTHRENE-8a-CARBOXYLIC ACID, ITS METHYL ESTER, AND (+/-)-(4abeta,8abeta10aalpha)-3,4,4a,6,7,8,8a,9,10,10a-New ursane-type triterpene with NO production suppressing activity from Nauclea officinalis.Opening or closing the lock? When reactivity is the key to biological activity.An efficient semi-synthesis and structure revision of a cytotoxic triterpenoid 25-acetoxy-3alpha-hydroxyolean-12-en-28-oic acid from Liquidamber styraciflua.Evaluation of the cytotoxic potential of a new pentacyclic triterpene from Rhododendron arboreum stem bark.Synthesis of new potential anticancer agents based on 4-thiazolidinone and oleanane scaffolds
P2860
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P2860
Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@ast
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@en
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@nl
type
label
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@ast
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@en
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@nl
prefLabel
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@ast
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@en
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@nl
P2093
P356
P1476
Novel synthetic oleanane and u ...... roduction in mouse macrophages
@en
P2093
B V Rounds
F G Favaloro
G W Gribble
H J Finlay
P304
P356
10.1021/JM000008J
P407
P577
2000-05-04T00:00:00Z