P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro - Wikidata - wikimedia - TriplyDB

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

http://www.wikidata.org/entity/Q28379179

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Inhibition of Tat activity by the HEXIM1 protein HIV-1 gene expression: lessons from provirus and non-integrated DNA Tat-SF1 protein associates with RAP30 and human SPT5 proteins Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro Structure and function of the human transcription elongation factor DSIF Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex Cyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9)-cyclin T1 interaction in Nef-dependent manner TRIM5α and Species Tropism of HIV/SIV The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription Identification of multiple cyclin subunits of human P-TEFb The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs PITALRE, the catalytic subunit of TAK, is required for human immunodeficiency virus Tat transactivation in vivo.Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter Domains in the SPT5 protein that modulate its transcriptional regulatory properties hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes 7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription Crystal structure of HIV-1 Tat complexed with human P-TEFb LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation Understanding HIV latency: the road to an HIV cure Physical interaction between pRb and cdk9/cyclinT2 complex Activation of MyoD-dependent transcription by cdk9/cyclin T2 Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes

P2860

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P2860

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

http://www.wikidata.org/entity/Q28379179

description

1997 nî lūn-bûn

@nan

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@ast

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@en

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@nl

type

label

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@ast

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@en

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@nl

prefLabel

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@ast

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@en

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

@nl

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Genes & Development

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P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

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C Blau

http://www.w3.org/2001/XMLSchema#string

D Hazuda

http://www.w3.org/2001/XMLSchema#string

G Lee

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H S Mancebo

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J Flygare

http://www.w3.org/2001/XMLSchema#string

J Peng

http://www.w3.org/2001/XMLSchema#string

J Tomassini

http://www.w3.org/2001/XMLSchema#string

O Flores

http://www.w3.org/2001/XMLSchema#string

P Luu

http://www.w3.org/2001/XMLSchema#string

Y Zhu

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P2860

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription

Novel mechanism and factor for regulation by HIV-1 Tat

Three functional classes of transcriptional activation domain

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function

Structure and functional properties of human general transcription factor IIE

Requirement for TFIIH kinase activity in transcription by RNA polymerase II

Cloning of a human gene encoding the general transcription initiation factor IIB

Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

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2633-2644

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scholarly article

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4705414

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10.1101/GAD.11.20.2633

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20

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11

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9334326

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316604

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