Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition

Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition

Item
http://www.wikidata.org/entity/Q28396027
Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyInactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells.Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Association between CHEK2 H371Y mutation and response to neoadjuvant chemotherapy in women with breast cancer.MYC is a critical target of FBXW7Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatmentSGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells.Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance.Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.BET bromodomain inhibitors synergize with ATR inhibitors in melanoma in melanomaBET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells.PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.c-MYC-induced genomic instability.
P2860

Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition

Item
http://www.wikidata.org/entity/Q28396027
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@ast
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@en
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@nl
type
label
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@ast
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@en
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@nl
prefLabel
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@ast
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@en
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P3181
P356
P1433
P1476
Chk2 deficiency in Myc overexp ...... mbination with PARP inhibition
@en
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P921
P932