Stimulus design for model selection and validation in cell signaling
about
Maximizing the information content of experiments in systems biologyReverse engineering and identification in systems biology: strategies, perspectives and challengesIn-vivo real-time control of protein expression from endogenous and synthetic gene networksOptimal experimental design for parameter estimation of a cell signaling modelParameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cellsBridging Mechanistic and Phenomenological Models of Complex Biological SystemsEmerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in OncologyA model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides.An integrated stochastic model of "inside-out" integrin activation and selective T-lymphocyte recruitment.Combining test statistics and models in bootstrapped model rejection: it is a balancing actRobust and efficient parameter estimation in dynamic models of biological systemsLaser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild typeDeveloping optimal input design strategies in cancer systems biology with applications to microfluidic device engineering.An iterative identification procedure for dynamic modeling of biochemical networksDiscriminating between rival biochemical network models: three approaches to optimal experiment design.Elucidating the in vivo phosphorylation dynamics of the ERK MAP kinase using quantitative proteomics data and Bayesian model selection.Nonparametric simulation of signal transduction networks with semi-synchronized updatePerspectives on tissue interactions in development and disease.Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network.An evolutionary firefly algorithm for the estimation of nonlinear biological model parametersSimultaneous model discrimination and parameter estimation in dynamic models of cellular systemsSimulating an infection growth model in certain healthy metabolic pathways of Homo sapiens for highlighting their role in Type I Diabetes mellitus using fire-spread strategy, feedbacks and sensitivitiesMultiple model-informed open-loop control of uncertain intracellular signaling dynamicsA Bayesian active learning strategy for sequential experimental design in systems biology.Efficient Optimization of Stimuli for Model-Based Design of Experiments to Resolve Dynamical Uncertainty.Iterative experiment design guides the characterization of a light-inducible gene expression circuitThe Limitations of Model-Based Experimental Design and Parameter Estimation in Sloppy Systems.Sloppy models, parameter uncertainty, and the role of experimental designPredicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway.Model-based design of experiments for cellular processes.Optimal design of stimulus experiments for robust discrimination of biochemical reaction networks.Experimental design schemes for learning Boolean network models.Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors.Dynamical modeling and multi-experiment fitting with PottersWheel.Real-time optogenetic control of intracellular protein concentration in microbial cell cultures.Multivariate moment closure techniques for stochastic kinetic models.CrossPlan: Systematic Planning of Genetic Crosses to Validate Mathematical Models.Practical limits for reverse engineering of dynamical systems: a statistical analysis of sensitivity and parameter inferability in systems biology models.Identification of Gene regulation models from single-cell data.Initial state perturbations as a validation method for data-driven fuzzy models of cellular networks
P2860
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P2860
Stimulus design for model selection and validation in cell signaling
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Stimulus design for model selection and validation in cell signaling
@ast
Stimulus design for model selection and validation in cell signaling
@en
Stimulus design for model selection and validation in cell signaling
@nl
type
label
Stimulus design for model selection and validation in cell signaling
@ast
Stimulus design for model selection and validation in cell signaling
@en
Stimulus design for model selection and validation in cell signaling
@nl
prefLabel
Stimulus design for model selection and validation in cell signaling
@ast
Stimulus design for model selection and validation in cell signaling
@en
Stimulus design for model selection and validation in cell signaling
@nl
P2860
P50
P3181
P1476
Stimulus design for model selection and validation in cell signaling
@en
P2093
Jared E Toettcher
Joshua F Apgar
P2860
P3181
P356
10.1371/JOURNAL.PCBI.0040030
P407
P577
2008-02-01T00:00:00Z