Investigating differential dynamics of the MAPK signaling cascade using a multi-parametric global sensitivity analysis

Investigating differential dynamics of the MAPK signaling cascade using a multi-parametric global sensitivity analysis

Item
http://www.wikidata.org/entity/Q28474802
Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology ModelsA model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen.Regulatory interactions maintaining self-renewal of human embryonic stem cells as revealed through a systems analysis of PI3K/AKT pathwayA mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection.Random parameter sampling of a generic three-tier MAPK cascade model reveals major factors affecting its versatile dynamics.Exploiting MEK inhibitor-mediated activation of ERα for therapeutic intervention in ER-positive ovarian carcinoma.Investigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated MacrophagesModel-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network.A General Network Pharmacodynamic Model-Based Design Pipeline for Customized Cancer Therapy Applied to the VEGFR Pathway.Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations.Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space.Least squares estimation in stochastic biochemical networks.Low concentration of formononetin promotes proliferation of estrogen receptor-positive cells through an ERα-miR-375-PTEN-ERK1/2-bcl-2 pathway.On the origin of bistability in the Stage 2 of the Huang-Ferrell model of the MAPK signaling.
P2860

Investigating differential dynamics of the MAPK signaling cascade using a multi-parametric global sensitivity analysis

Item
http://www.wikidata.org/entity/Q28474802
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Investigating differential dyn ...... ic global sensitivity analysis
@ast
Investigating differential dyn ...... ic global sensitivity analysis
@en
Investigating differential dyn ...... ic global sensitivity analysis
@nl
type
label
Investigating differential dyn ...... ic global sensitivity analysis
@ast
Investigating differential dyn ...... ic global sensitivity analysis
@en
Investigating differential dyn ...... ic global sensitivity analysis
@nl
prefLabel
Investigating differential dyn ...... ic global sensitivity analysis
@ast
Investigating differential dyn ...... ic global sensitivity analysis
@en
Investigating differential dyn ...... ic global sensitivity analysis
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P932
P3181
P356
P1433
P1476
Investigating differential dyn ...... ic global sensitivity analysis
@en
P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PONE.0004560
P407
P433
P478
P577
P5875
P698
P932