A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen
about
Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungsMultiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approachMycobacterium tuberculosis: Manipulator of Protective ImmunityHeterogeneity in tuberculosis pathology, microenvironments and therapeutic responsesTranslating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosisStructure, dynamics, and interaction of Mycobacterium tuberculosis (Mtb) DprE1 and DprE2 examined by molecular modeling, simulation, and electrostatic studiesGenomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b.Identification of a small molecule with activity against drug-resistant and persistent tuberculosisMycobacterium tuberculosis Transcription Machinery: Ready To Respond to Host AttacksPortrait of a pathogen: the Mycobacterium tuberculosis proteome in vivoMetabolic regulation of mycobacterial growth and antibiotic sensitivityMycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophagesMmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growthAn acyl-CoA synthetase in Mycobacterium tuberculosis involved in triacylglycerol accumulation during dormancyReplication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibilityHigh Persister Mutants in Mycobacterium tuberculosisMycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosisA computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatmentThree-dimensional in vitro models of granuloma to study bacteria-host interactions, drug-susceptibility, and resuscitation of dormant mycobacteriaSimple model for testing drugs against nonreplicating Mycobacterium tuberculosisLipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel "Mtb LipidDB"Mycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite StressAcid stress response of a mycobacterial proteome: insight from a gene ontology analysisPopulations of latent Mycobacterium tuberculosis lack a cell wall: Isolation, visualization, and whole-genome characterizationLipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin.Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism.Mycobacterium tuberculosis wears what it eatsScreening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.Gene expression profiling of Mycobacterium avium subsp. paratuberculosis in simulated multi-stress conditions and within THP-1 cells reveals a new kind of interactive intramacrophage behaviour.Latent tuberculosis infection: myths, models, and molecular mechanismsMycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafishPotassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.Wax ester synthesis is required for Mycobacterium tuberculosis to enter in vitro dormancy.Different transcriptional profiles of RAW264.7 infected with Mycobacterium tuberculosis H37Rv and BCG identified via deep sequencingHuman granuloma in vitro model, for TB dormancy and resuscitation.Carbon flux rerouting during Mycobacterium tuberculosis growth arrest.Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay.Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues.Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation modelIdentification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis.
P2860
Q21089606-EC963BB4-2483-4E79-B86B-535F0857F1CBQ21090008-E81A20E2-7AB2-4477-9072-CD98118B35D9Q26765471-D688EDAB-C575-4198-A4D9-4E83ED59DC34Q26823503-615BF7EB-E446-4FF2-A5A0-CC0E3776A97DQ26824812-8CB1467D-1AB3-4F1F-949D-AE465C62AD0DQ27311652-797AF865-314C-4502-98AA-F96C5641FB2AQ27316642-CF0F0EE1-CE78-4214-B3E4-29A7643CF33DQ27678663-12C7F7EF-6FE8-4948-91DF-2C8A2994718DQ28071015-257BFB68-38B6-4F51-B616-2D63107640D7Q28476108-BFA9AF9D-4672-45BE-95D7-18F751399D5CQ28478251-202008B5-C1D5-4B90-9545-A9E48535A481Q28478716-71E5BDA4-4575-413E-AEEE-AA424AFE07F0Q28484106-004BBE3D-E521-40FF-AAE8-5FE7EEFFECBAQ28542621-648D7F97-FB9A-47A9-A063-7086DFDFA863Q28544850-7D47BE15-0799-4FFC-B38C-400D92FDADB5Q28552067-7F443A19-D9A4-4F70-ADE4-145BB68EBDE6Q28552338-1D69D97E-532F-43B8-AD89-AF113DA03B8CQ28649754-73F9C177-6259-4591-89F5-6E4DD1FDBE44Q28658279-337652E9-4688-41A2-843B-F067C14ABF99Q30496706-CA56D1AA-B994-4118-B138-466B76A90AEAQ30499399-0D4A210D-5C5A-4E9B-8AE5-CC96EE893D26Q30842403-7F5C6027-4A41-41A8-93C6-FB8DA1BB4A2AQ33573005-A65B05EF-B40B-457F-B7C0-B1C6F57527AAQ33725460-9FF2023F-F843-4B53-887E-1EF00FEAB307Q33967392-BB8417F6-E0E8-432E-85B5-7FDB971291C3Q34033091-0D30C82E-9231-49F5-B29A-78C1015FD29EQ34089860-29B9909F-0AE6-4FD5-BE53-8E25656EB105Q34241120-D636155E-7954-4AC2-A4F4-3143D11EE5DFQ34285993-30A9C11E-5FD3-4E5F-9970-C9D03000E9AAQ34297816-322168B9-E3E9-4B42-9C3D-46C723D002CBQ34426515-B6555A10-62BF-4A0F-BF29-B5E51DDBEA13Q34461036-47001BFD-416D-455E-8217-1F162B47F7A5Q34525403-1CE67542-BCEA-4FBE-BD1F-36A93499DE80Q34532687-984D6A39-58A1-4CCB-B760-B49B5504097CQ34545296-DA8168B3-A982-4D4B-BD23-EAD52B11F057Q34768891-A28F9447-51B7-4E1F-A1D7-E95ECE2A13AFQ34781823-EE77BDC6-2529-4B86-A620-C2C69D5C5BA4Q34872376-D8E0A71F-CCD0-4D9E-A44C-1D5313C2A81FQ34881104-3447CCB3-56ED-45BE-99EE-82A024F555E9Q34903880-C1E1A959-A057-4D39-8FA3-ABADFBFEE3DA
P2860
A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@ast
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@en
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@nl
type
label
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@ast
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@en
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@nl
prefLabel
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@ast
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@en
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@nl
P2093
P2860
P3181
P1433
P1476
A novel in vitro multiple-stre ...... rug-tolerant, dormant pathogen
@en
P2093
Bassam Abomoelak
Chang-Muk Lee
Chirajyoti Deb
Jaiyanth Daniel
Linda Rogers
Pappachan E Kolattukudy
Santosh Pawar
Tatiana D Sirakova
Vinod S Dubey
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006077
P407
P577
2009-06-29T00:00:00Z