Mitral cells of the olfactory bulb perform metabolic sensing and are disrupted by obesity at the level of the Kv1.3 ion channel
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Ion Channels in Obesity: Pathophysiology and Potential Therapeutic TargetsUbiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targetingHyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning.Mature and precursor brain-derived neurotrophic factor have individual roles in the mouse olfactory bulbOlfaction under metabolic influences.Diet-induced obesity resistance of Kv1.3-/- mice is olfactory bulb dependent.Hypothalamus-olfactory system crosstalk: orexin a immunostaining in mice.Olfactory ability and object memory in three mouse models of varying body weight, metabolic hormones, and adiposity.The incretin hormone glucagon-like peptide 1 increases mitral cell excitability by decreasing conductance of a voltage-dependent potassium channel.Mitochondrial Ultrastructure and Glucose Signaling Pathways Attributed to the Kv1.3 Ion Channel.Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance.Margatoxin-bound quantum dots as a novel inhibitor of the voltage-gated ion channel Kv1.3.Insulin modulates network activity in olfactory bulb slices: impact on odour processing.Awake, long-term intranasal insulin treatment does not affect object memory, odor discrimination, or reversal learning in mice.Greater excitability and firing irregularity of tufted cells underlies distinct afferent-evoked activity of olfactory bulb mitral and tufted cells.Nutrient Sensing: Another Chemosensitivity of the Olfactory System.High Fructose Diet inducing diabetes rapidly impacts olfactory epithelium and behavior in miceAfterhyperpolarization (AHP) regulates the frequency and timing of action potentials in the mitral cells of the olfactory bulb: role of olfactory experience.Neuromodulation in Chemosensory Pathways.Insulin Modulates Neural Activity of Pyramidal Neurons in the Anterior Piriform Cortex.Association between diabetes mellitus and olfactory dysfunction: current perspectives and future directions.Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage-gated potassium channel.Differential serotonergic modulation across the main and accessory olfactory bulbs.Internal State Dependent Odor Processing and Perception-The Role of Neuromodulation in the Fly Olfactory System.Long-Lasting Metabolic Imbalance Related to Obesity Alters Olfactory Tissue Homeostasis and Impairs Olfactory-Driven Behaviors.Elevated Anxiety and Impaired Attention in Super-Smeller, Kv1.3 Knockout Mice.The Effects of High Fat Diet-Induced Stress on Olfactory Sensitivity, Behaviors, and Transcriptional Profiling in
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P2860
Mitral cells of the olfactory bulb perform metabolic sensing and are disrupted by obesity at the level of the Kv1.3 ion channel
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2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@ast
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
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Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
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Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@ast
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@en
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@nl
prefLabel
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@ast
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@en
Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@nl
P2093
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Mitral cells of the olfactory ...... level of the Kv1.3 ion channel
@en
P2093
Debra Ann Fadool
Kristal Tucker
Paola Pedarzani
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P304
P3181
P356
10.1371/JOURNAL.PONE.0024921
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P577
2011-01-01T00:00:00Z