Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS

Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS

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http://www.wikidata.org/entity/Q28477331
Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperaturesOxidation in the complementarity-determining regions differentially influences the properties of therapeutic antibodiesFunctional assessment of antibody oxidation by native mass spectrometry.Biosensor binding data and its applicability to the determination of active concentration.Oxidation of therapeutic proteins and peptides: structural and biological consequences.Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes.Biopharmaceutical Informatics: supporting biologic drug development via molecular modelling and informatics.Novel chemical degradation pathways of proteins mediated by tryptophan oxidation: tryptophan side chain fragmentation.Molecular polygamy: The promiscuity of l-phenylalanyl-tRNA-synthetase triggers misincorporation of meta- and ortho-tyrosine in monoclonal antibodies expressed by Chinese hamster ovary cells.Chemically defined media modifications to lower tryptophan oxidation of biopharmaceuticals.8(th) Annual European Antibody Congress 2012: November 27-28, 2012, Geneva, Switzerland.Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions
P2860

Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS

Item
http://www.wikidata.org/entity/Q28477331
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Identification of potential si ...... eroxide and quantitative LC-MS
@ast
Identification of potential si ...... eroxide and quantitative LC-MS
@en
Identification of potential si ...... eroxide and quantitative LC-MS
@nl
type
label
Identification of potential si ...... eroxide and quantitative LC-MS
@ast
Identification of potential si ...... eroxide and quantitative LC-MS
@en
Identification of potential si ...... eroxide and quantitative LC-MS
@nl
prefLabel
Identification of potential si ...... eroxide and quantitative LC-MS
@ast
Identification of potential si ...... eroxide and quantitative LC-MS
@en
Identification of potential si ...... eroxide and quantitative LC-MS
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P3181
P356
P1433
P1476
Identification of potential si ...... eroxide and quantitative LC-MS
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P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PONE.0017708
P407
P433
P478
P50
P577
P5875
P698
P921
P932