Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease
about
Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrinHepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient miceCharacterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibodyNiemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver functionOntogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease.Current controversies in Niemann-Pick C1 disease: steroids or gangliosides; neurons or neurons and glia.Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications.SpatTrack: an imaging toolbox for analysis of vesicle motility and distribution in living cells.Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells.Niemann-Pick type C2 protein supplementation in experimental non-alcoholic fatty liver disease.
P2860
Q33945068-02C39006-8544-49F7-A4F0-782366249F58Q34356070-224E45D9-2E86-4293-9111-6DC28D80C3D9Q35023240-952FD48D-F684-49CE-85B3-4B2AD01F6148Q35660156-8434128D-6DAE-46DD-ADFF-E2C8E443C1A2Q35920269-12F26F30-BE1A-4C8E-9A84-DAD41B72EF50Q37360639-64F0920E-E78A-4562-8349-919DD3A381ADQ38071990-A4031263-B8FC-46A0-8E92-6548A28A407BQ38901858-5C2EAF6A-BE85-4A4E-8CA7-6E4F9823E5D6Q38954364-55988EE7-1197-47E1-8BD5-9EBA2D988AF4Q39732986-303C50B5-BA40-4DB2-B0BF-F1A302C5642EQ54095552-22A3380F-4915-4DA3-9682-E718DD95BABF
P2860
Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@ast
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@en
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@nl
type
label
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@ast
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@en
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@nl
prefLabel
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@ast
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@en
Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@nl
P2093
P2860
P3181
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Protein replacement therapy pa ...... f Niemann-Pick type C2 disease
@en
P2093
Christian Würtz Heegaard
Derek Symula
Frederik Dagnaes-Hansen
Gitte Krogh Nielsen
Ida Elisabeth Holm
Niels Trolle Andersen
Steve Meaney
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0027287
P407
P577
2011-01-01T00:00:00Z