Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools
about
Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency.Hug1 is an intrinsically disordered protein that inhibits ribonucleotide reductase activity by directly binding Rnr2 subunit.UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools.Genetic instability in budding and fission yeast-sources and mechanismsDepletion of cellular iron by curcumin leads to alteration in histone acetylation and degradation of Sml1p in Saccharomyces cerevisiaeA network of HMG-box transcription factors regulates sexual cycle in the fungus Podospora anserina.Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiencyLoss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutantsGenome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae.Leveraging DNA damage response signaling to identify yeast genes controlling genome stability.Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelitydNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotypeS phase block following MEC1ATR inactivation occurs without severe dNTP depletion.Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.Telomere length homeostasis responds to changes in intracellular dNTP pools.Molecular basis of the essential s phase function of the rad53 checkpoint kinase.Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation.The Intra-S Checkpoint Responses to DNA Damage.The yeast hypoxic responses, resources for new biotechnological opportunities.Deoxyribonucleotides as genetic and metabolic regulatorsDeoxyribonucleotide metabolism, mutagenesis and cancer.DNA damage induced by the anticodon nuclease from a Pichia acaciae killer strain is linked to ribonucleotide reductase depletion.Pre-activation of the genome integrity checkpoint increases DNA damage toleranceRnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage.Checkpoint-dependent RNR induction promotes fork restart after replicative stress.Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin.The elemental role of iron in DNA synthesis and repair.Spatial separation between replisome- and template-induced replication stress signaling.
P2860
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P2860
Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools
description
2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@ast
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@en
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@nl
type
label
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@ast
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@en
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@nl
prefLabel
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@ast
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@en
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@nl
P2093
P2860
P1433
P1476
Ixr1 is required for the expre ...... and maintenance of dNTP pools
@en
P2093
Andrei Chabes
Emad Barsoum
Olga Tsaponina
Stefan U Aström
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002061
P407
P577
2011-05-01T00:00:00Z