A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
about
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Carcinoma-associated fibroblasts are a promising therapeutic target.Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer.Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile.Hedgehog pathway inhibitors: a patent review (2009--present).Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal.Sonic hedgehog signaling in kidney fibrosis: a master communicator.Discovery of inhibitors of the Wnt and Hedgehog signaling pathways through the catalytic enantioselective synthesis of an iridoid-inspired compound collection.Strategies to target the Hedgehog signaling pathway for cancer therapy.Catalytic enantioselective synthesis of functionalized tropanes reveals novel inhibitors of hedgehog signaling.Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling
P2860
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P2860
A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@ast
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@en
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@nl
type
label
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@ast
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@en
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@nl
prefLabel
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@ast
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@en
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@nl
P2093
P2860
P1433
P1476
A novel synthetic smoothened a ...... ma xenografts in a mouse model
@en
P2093
Alexander Khvat
Daniel D Holsworth
Dirk Petersen
Martin F Strand
Stefan Krauss
P2860
P304
P356
10.1371/JOURNAL.PONE.0019904
P407
P577
2011-01-01T00:00:00Z