The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium - Wikidata - wikimedia - TriplyDB

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium

http://www.wikidata.org/entity/Q28482106

about

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration Sarpogrelate, a 5-HT2A Receptor Antagonist, Protects the Retina From Light-Induced Retinopathy Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death.Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium.Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.Aging is not a disease: distinguishing age-related macular degeneration from aging.Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina.A case for neuroprotection in ophthalmology: developments in translational research.Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.Studying melanin and lipofuscin in RPE cell culture models.Repurposing an orally available drug for the treatment of geographic atrophy.Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress Autophagy regulating kinases as potential therapeutic targets for age-related macular degeneration.Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration.Evaluation of buspirone on streptozotocin induced type 1 diabetes and its associated complications.Retinal Toxicity Induced by a Novel β-secretase Inhibitor in the Sprague-Dawley Rat.The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection.

P2860

Q27008407-1B9280E2-B270-47FA-B7D2-869F8E485FE6 Q27334961-AA8F18B6-2467-4CB9-A28C-3991DF3633F1 Q28552843-071F66B0-E73B-4F15-BD5C-0CB209E99233 Q33957336-A6000EB5-F17E-4592-B57F-FDC1BF6B65CF Q34738110-9098D942-893E-4995-BADB-8A138CBE019F Q35555144-C0177DFD-8C90-4430-9DA8-3946243AE843 Q35852752-E58BA070-9FED-4D0A-A801-B5086D8735C2 Q36165326-C4F0F9B0-1A45-4A3A-8E98-29F97BF9A538 Q37256088-2C89E5AE-260A-4F1F-BC76-028A3F1BB68B Q37315838-4129C934-D6B1-434E-9795-8692A2EA4523 Q37645117-0F916AF4-65DF-4060-993F-D02DF135B71E Q37680649-B2AF6D02-D68D-4D8D-9835-FDFEC269F22B Q37682509-30C32897-60DC-4D9A-B95D-B79B0BDBAFA6 Q38242789-7512DEDE-C12B-40FD-865E-6D7E9B5A53E0 Q38775689-0B3B1035-4676-4904-96E9-7774495F08CB Q38840174-C7E71E4A-C7F0-4C80-9570-180B784450E4 Q39512471-09C37148-9CF6-4AFA-B661-495FF44EC65C Q40334518-97C71C07-B2EB-4749-AD0E-708B7074D671 Q41921965-FB80483D-92E6-4A1B-8140-845FCB017E6A Q46429003-0EAFCF59-AF23-4326-B502-E0E01CB9A073 Q49177877-9E5CBE48-28D8-437B-A899-586203DBD1DC

P2860

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium

http://www.wikidata.org/entity/Q28482106

description

2012 nî lūn-bûn

@nan

2012 թուականին հրատարակուած գիտական յօդուած

@hyw

2012 թվականին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

name

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@ast

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@en

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@nl

type

label

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@ast

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@en

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@nl

prefLabel

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@ast

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@en

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@nl

P1433

Q28482106-10A553C7-03EE-4D71-A31F-23F42A17C23D

P1476

Q28482106-1C1E24CD-4B40-4F89-AB16-E17F0B3AD9A6

P2093

Q28482106-19963104-1036-42E2-B015-CF5B217BBCDE

Q28482106-23DC36B7-80B4-4A7B-8AA6-5D64B0413370

Q28482106-2BF15E10-E7D9-4E5C-AB20-6CF242530830

Q28482106-31A81B6F-1087-43F3-A491-3F9436D7B532

Q28482106-39E57598-C2F2-4B6F-885E-935722B7AF3C

Q28482106-3E72F727-9E13-4F8D-A932-D53B61150EC5

Q28482106-863F72D6-5D2C-43DE-85BC-F58451F68A59

Q28482106-8D5C8BEC-B93A-472B-BAFD-2AE98686759C

Q28482106-B23F6F96-5FA1-45AA-AFD0-4FDA1B43D1EF

Q28482106-F4BCDA82-4003-4646-92C9-FAAE4E33FDA1

P2860

Q28482106-024DF7A0-CC67-4702-A411-60F3D2713B03

Q28482106-1183E8E8-9DB1-4B6B-8EE6-A75752431D48

Q28482106-1244FD6F-6C87-4A20-9FEE-674ED25F15D6

Q28482106-198405F9-8E31-4F40-830D-F3792280B562

Q28482106-19A312A3-0A8A-4214-8701-646649149E7F

Q28482106-2C10667A-139F-4587-9D1A-F48759E22940

Q28482106-3127A2AB-CA96-4688-8392-22EF3DD51ADF

Q28482106-350786E6-C484-4D85-B409-1FFB6F3E8E8E

Q28482106-36E60C6B-E466-4B2E-B28F-1A06999693E1

Q28482106-36F349D0-E90C-4F3E-8DDA-CECDD2C24DCC

P304

Q28482106-37AC858E-88F4-4342-9F69-3DC6A6695181

P31

Q28482106-1BC84FD5-06E6-468B-969B-24C1BA6EDC9D

P3181

Q28482106-9876743A-12B7-43D6-82B9-309D6C857689

P356

Q28482106-B7164042-7BFE-4D5D-A29B-7237D8E4F4D6

P407

Q28482106-762AE3E1-0B67-4A67-BC42-AE480CA1430B

P433

Q28482106-A8426EC5-3102-4801-879A-C59D59A3CBB9

P478

Q28482106-2F61225C-9F94-472F-9A1B-46AFC6425FF4

P50

Q28482106-C7D6687E-98EC-4C7E-98A8-3424E9D88989

P577

Q28482106-0980A030-8FE7-4847-8CAF-AA5450E997AC

P5875

Q28482106-71C305E8-C37A-4E24-8A93-469873C068A2

P698

Q28482106-6117B8D6-C1A1-417F-85C0-9D5CA066D8FC

P932

Q28482106-0E8084D5-54A1-4A92-AF05-49FC8B9B9E92

P3181

P356

JOURNAL.PONE.0034468

P1433

P1476

The 5HT1a receptor agonist 8-O ...... the retinal pigment epithelium

@en

P2093

Carl Romano

http://www.w3.org/2001/XMLSchema#string

Haoyu Mao

http://www.w3.org/2001/XMLSchema#string

Haripriya Vittal Rao

http://www.w3.org/2001/XMLSchema#string

Hong Li

http://www.w3.org/2001/XMLSchema#string

Jun Cai

http://www.w3.org/2001/XMLSchema#string

Michael E Boulton

http://www.w3.org/2001/XMLSchema#string

Prajitha Thampi

http://www.w3.org/2001/XMLSchema#string

Sayak K Mitter

http://www.w3.org/2001/XMLSchema#string

Soojung Seo

http://www.w3.org/2001/XMLSchema#string

Xiaoping Qi

http://www.w3.org/2001/XMLSchema#string

P2860

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

The effects of ethanol and the serotonin(1A) agonist ipsapirone on the expression of the serotonin(1A) receptor and several antiapoptotic proteins in fetal rhombencephalic neurons

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

Prevalence of age-related macular degeneration in the United States

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

Subretinal injections in rodent eyes: effects on electrophysiology and histology of rat retina.

Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration.

Fundus autofluorescence in patients with age-related macular degeneration and high risk of visual loss.

Distribution of pigment epithelium autofluorescence in retinal disease state recorded in vivo and its change over time.

Fundus autofluorescence and fundus perimetry in the junctional zone of geographic atrophy in patients with age-related macular degeneration.

P304

e34468

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4443321

http://www.w3.org/2001/XMLSchema#string

P356

10.1371/JOURNAL.PONE.0034468

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

Alfred S. Lewin

P577

2012-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

224053207

http://www.w3.org/2001/XMLSchema#string

P698

22509307

http://www.w3.org/2001/XMLSchema#string

P932

3317995

http://www.w3.org/2001/XMLSchema#string