Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer
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Cancer stem cells in small cell lung cancerFunctions of lncRNA HOTAIR in lung cancerKDM1 class flavin-dependent protein lysine demethylasesLSD1 inhibition: a therapeutic strategy in cancer?Over-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-cateninOverexpression of deubiquitinating enzyme USP28 promoted non-small cell lung cancer growthIdentification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cellsEpigenetic regulation of epithelial-mesenchymal transitionMelatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models.USP22 is useful as a novel molecular marker for predicting disease progression and patient prognosis of oral squamous cell carcinomaLysine-specific demethylase 1 in breast cancer cells contributes to the production of endogenous formaldehyde in the metastatic bone cancer pain model of rats.Histone Demethylases in Colon Cancer.Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/β-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibitionCoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer.Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer.Status of epigenetic chromatin modification enzymes and esophageal squamous cell carcinoma risk in northeast Indian population.Prognostic role of LSD1 in various cancers: evidence from a meta-analysisLysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells.Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients.Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer.A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.Downregulation of LSD1 suppresses the proliferation, tumorigenicity and invasion of papillary thyroid carcinoma K1 cells.Epigenetic regulation of LSD1 during mammary carcinogenesis.Long non-coding RNA LINC01133 represses KLF2, P21 and E-cadherin transcription through binding with EZH2, LSD1 in non small cell lung cancer.Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells.Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancerUpregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancerKDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells.Role of HOTAIR in the diagnosis and prognosis of acute leukemia.Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent.LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter.Histone demethylase PHF8 promotes progression and metastasis of gastric cancer.Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells.Epigenetic therapy in non-small-cell lung cancer: targeting DNA methyltransferases and histone deacetylases.Pre-clinical studies of epigenetic therapies targeting histone modifiers in lung cancer.
P2860
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P2860
Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
@yue
name
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@ast
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@en
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@nl
type
label
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@ast
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@en
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@nl
prefLabel
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@ast
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@en
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@nl
P2093
P2860
P3181
P1433
P1476
Over-expression of LSD1 promot ...... in non-small cell lung cancer
@en
P2093
Dongmei Yuan
Tangfeng Lv
Xiaohui Miao
Xiaokun Shen
Yanling Lv
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0035065
P407
P577
2012-01-01T00:00:00Z