JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21

JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21

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http://www.wikidata.org/entity/Q28482983
Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinomaSelective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapAIdentification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapySynthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents.Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus.Harmine Hydrochloride Triggers G2 Phase Arrest and Apoptosis in MGC-803 Cells and SMMC-7721 Cells by Upregulating p21, Activating Caspase-8/Bid, and Downregulating ERK/Bad Pathway.HIF-α Promotes Chronic Myelogenous Leukemia Cell Proliferation by Upregulating p21 Expression.Toxic effects of mildly elevated homocysteine concentrations in neuronal-like cells.Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells.Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen.Hypoxia-Inducible Factor 1-Alpha Regulates Cancer-Inhibitory Effect of Human Mesenchymal Stem Cells.
P2860

JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21

Item
http://www.wikidata.org/entity/Q28482983
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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type
label
JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
@ast
JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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prefLabel
JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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JKA97, a novel benzylidene ana ...... dependent up-regulation of p21
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P2860
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P3181
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10.1371/JOURNAL.PONE.0034303
P407
P433
P478
P50
P577
P5875
P698
P932