about
Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsJKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.Natural product MDM2 inhibitors: anticancer activity and mechanisms of action.A quantitative LC-MS/MS method for determination of SP-141, a novel pyrido[b]indole anticancer agent, and its application to a mouse PK study.Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2.RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo.Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action.RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy.Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapAThe MDM2-p53 pathway revisitedIdentification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapyInulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapyChemical constituents of plants from the genus Dracocephalum.miRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents.Inula sesquiterpenoids: structural diversity, cytotoxicity and anti-tumor activity.Japonicone A suppresses growth of Burkitt lymphoma cells through its effect on NF-κB.Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.New glycosides from Dracocephalum tanguticum maxim.Two new monoterpene alkaloid derivatives from the roots of Incarvillea arguta.Four new sesquiterpenoids from the roots of Incarvillea arguta and their inhibitory activities against lipopolysaccharide-induced nitric oxide production.Blumeaenes A-J, sesquiterpenoid esters from Blumea balsamifera with NO inhibitory activity.A new ent-kaurane type diterpenoid glycoside from Inula japonica Thunb.A new triterpenoid from Brucea javanica.Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica Thunb.Oral delivery of anti-MDM2 inhibitor SP141-loaded FcRn-targeted nanoparticles to treat breast cancer and metastasis.Japonicone A antagonizes the activity of TNF-α by directly targeting this cytokine and selectively disrupting its interaction with TNF receptor-1.Japonicones Q-T, four new dimeric sesquiterpene lactones from Inula japonica Thunb.Argutalactone, an unprecedented sesquiterpenoid lactone with a 6/5/7 tricyclic system from Incarvillea arguta.Sesquiterpene lactones from Inula helianthus-aquatica.Sesquiterpenoids from Inula lineariifolia inhibit nitric oxide production.Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen.Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy.Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes.Bioactive eudesmane and germacrane derivatives from Inula wissmanniana Hand.-Mazz.Experimental Therapy of Advanced Breast Cancer: Targeting NFAT1-MDM2-p53 Pathway.Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agentSTAT3 as a potential therapeutic target in triple negative breast cancer: a systematic reviewPrevention of prostate cancer by natural product MDM2 inhibitor GS25: In vitro and in vivo activities and molecular mechanisms
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description
researcher ORCID ID = 0000-0002-8559-616X
@en
wetenschapper
@nl
name
Jiangjiang Qin
@ast
Jiangjiang Qin
@en
Jiangjiang Qin
@es
Jiangjiang Qin
@nl
type
label
Jiangjiang Qin
@ast
Jiangjiang Qin
@en
Jiangjiang Qin
@es
Jiangjiang Qin
@nl
prefLabel
Jiangjiang Qin
@ast
Jiangjiang Qin
@en
Jiangjiang Qin
@es
Jiangjiang Qin
@nl
P31
P496
0000-0002-8559-616X