Antifungal drug discovery: something old and something new
about
Bioprospecting Sponge-Associated Microbes for Antimicrobial CompoundsReactive oxygen species-inducing antifungal agents and their activity against fungal biofilmsPost-PKS tailoring steps of a disaccharide-containing polyene NPP in Pseudonocardia autotrophicaLabel-free Chemical Imaging of Fungal Spore Walls by Raman Microscopy and Multivariate Curve Resolution AnalysisInteraction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber matsSynthesis and Antimicrobial Activities of His(2-aryl)-Arg and Trp-His(2-aryl) Classes of Dipeptidomimetics.Structure-activity relationship study of the plant-derived decapeptide OSIP108 inhibiting Candida albicans biofilm formation.Antifungal drug discovery: the process and outcomes.Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection.A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosisIdentification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans.The synthetic amphipathic peptidomimetic LTX109 is a potent fungicide that disturbs plasma membrane integrity in a sphingolipid dependent mannerRepurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms.Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.Velvet-mediated repression of β-glucan synthesis in Aspergillus nidulans sporesStructure-activity relationships for the antifungal activity of selective estrogen receptor antagonists related to tamoxifenEssential gene discovery in the basidiomycete Cryptococcus neoformans for antifungal drug target prioritizationEbselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells.Noncanoncial signal recognition particle RNAs in a major eukaryotic phylum revealed by purification of SRP from the human pathogen Cryptococcus neoformansRepurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 PathwayHigh-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance.Reconstruction and applications of consensus yeast metabolic network based on RNA sequencing.Collaborative Total Synthesis: Routes to (±)-Hippolachnin A Enabled by Quadricyclane Cycloaddition and Late-Stage C-H OxidationA complex game of hide and seek: the search for new antifungalsStructure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agentsCranberry-derived proanthocyanidins prevent formation of Candida albicans biofilms in artificial urine through biofilm- and adherence-specific mechanisms.Antifungal Therapy for Systemic Mycosis and the Nanobiotechnology Era: Improving Efficacy, Biodistribution and Toxicity.Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi.Antifungal adjuvants: Preserving and extending the antifungal arsenalAntifungal drug development: challenges, unmet clinical needs, and new approaches.Early state research on antifungal natural products.Strategies in the discovery of novel antifungal scaffolds.Trehalose pathway as an antifungal target.Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity.Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development.The antifungal pipeline: a reality check.Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi.Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi.High-Throughput Screen in Cryptococcus neoformans Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling.Clinical evaluation of the antifungal effect of sertraline in the treatment of cryptococcal meningitis in HIV patients: a single Mexican center experience.
P2860
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P2860
Antifungal drug discovery: something old and something new
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Antifungal drug discovery: something old and something new
@ast
Antifungal drug discovery: something old and something new
@en
Antifungal drug discovery: something old and something new
@nl
type
label
Antifungal drug discovery: something old and something new
@ast
Antifungal drug discovery: something old and something new
@en
Antifungal drug discovery: something old and something new
@nl
prefLabel
Antifungal drug discovery: something old and something new
@ast
Antifungal drug discovery: something old and something new
@en
Antifungal drug discovery: something old and something new
@nl
P2860
P3181
P1433
P1476
Antifungal drug discovery: something old and something new
@en
P2093
Arielle Butts
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002870
P407
P577
2012-09-06T00:00:00Z