Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.
about
Antifungal drug discovery: something old and something newSiderophores; iron scavengers: the novel & promising targets for pathogen specific antifungal therapy.Pharmacodynamic target evaluation of a novel oral glucan synthase inhibitor, SCY-078 (MK-3118), using an in vivo murine invasive candidiasis model.Topological and mutational analysis of Saccharomyces cerevisiae Fks1A complex game of hide and seek: the search for new antifungalsAntifungal drug development: challenges, unmet clinical needs, and new approaches.Systemic Antifungal Agents: Current Status and Projected Future Developments.New facets of antifungal therapy.Strategies in the discovery of novel antifungal scaffolds.The antifungal pipeline: a reality check.Antifungal resistance and new strategies to control fungal infections.Drugs in Clinical Development for Fungal Infections.Antifungal Activity of SCY-078 and Standard Antifungal Agents Against 178 Clinical Isolates of Resistant and Susceptible Candida Species.Differential Activity of the Oral Glucan Synthase Inhibitor SCY-078 against Wild-Type and Echinocandin-Resistant Strains of Candida Species.In vitro activity of a new oral glucan synthase inhibitor (MK-3118) tested against Aspergillus spp. by CLSI and EUCAST broth microdilution methodsTulbaghia violacea Harv. plant extract affects cell wall synthesis in Aspergillus flavus.Genetic alteration of UDP-rhamnose metabolism in Botrytis cinerea leads to the accumulation of UDP-KDG that adversely affects development and pathogenicity.Review on fungal enzyme inhibitors – potential drug targets to manage human fungal infectionsMycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products
P2860
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P2860
Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@ast
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@en
type
label
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@ast
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@en
prefLabel
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@ast
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@en
P2093
P2860
P356
P1476
Discovery of a novel class of ...... -D-glucan synthase inhibitors.
@en
P2093
Andrew Chau
Anthony Cacciapuoti
Barry Antonacci
Cara Mendrick
Christine Norris
Ilias Triantafyllou
Maya Gurnani
Michelle F Waldman
Nathaniel Brown
Nicholas Bauman
P2860
P304
P356
10.1128/AAC.00432-11
P407
P577
2011-08-15T00:00:00Z