Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
about
Biotin synthesis begins by hijacking the fatty acid synthetic pathwayCarboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductaseBacterial lipids: metabolism and membrane homeostasisThe crystal structure of a mammalian fatty acid synthaseThe Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial ParasitesMode of Action, In Vitro Activity, and In Vivo Efficacy of AFN-1252, a Selective Antistaphylococcal FabI InhibitorDetermination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzaeStructure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone InhibitorsStructural and Enzymatic Analyses Reveal the Binding Mode of a Novel Series of Francisella tularensis Enoyl Reductase (FabI) InhibitorsStructures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanismRational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase InhibitorResistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) AntibioticsThe Vibrio cholerae fatty acid regulatory protein, FadR, represses transcription of plsB, the gene encoding the first enzyme of membrane phospholipid biosynthesisMechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia malleiTriclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductaseChallenges of antibacterial discoveryComplex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters.Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matchingStaphylococcus epidermidis isolated in 1965 are more susceptible to triclosan than current isolates.The impact of triclosan on the spread of antibiotic resistance in the environment.Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of β-oxidation cycleMeleagrin, a new FabI inhibitor from Penicillium chryosogenum with at least one additional mode of action.Perturbation and restoration of the fathead minnow gut microbiome after low-level triclosan exposure.Identification of a conserved protein involved in anaerobic unsaturated fatty acid synthesis in Neiserria gonorrhoeae: implications for facultative and obligate anaerobes that lack FabA.FabV/Triclosan Is an Antibiotic-Free and Cost-Effective Selection System for Efficient Maintenance of High and Medium-Copy Number Plasmids in Escherichia coli.Crystallization and preliminary X-ray crystallographic studies of a new class of enoyl-(acyl-carrier protein) reductase, FabV, from Vibrio fischeriExpression, purification and characterization of enoyl-ACP reductase II, FabK, from Porphyromonas gingivalis.Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP.Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistanceTriclosan Resistome from Metagenome Reveals Diverse Enoyl Acyl Carrier Protein Reductases and Selective Enrichment of Triclosan Resistance Genes.Diversity in enoyl-acyl carrier protein reductases.Resistance to AFN-1252 arises from missense mutations in Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI).Enoyl-Acyl Carrier Protein Reductase I (FabI) Is Essential for the Intracellular Growth of Listeria monocytogenes.Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.The Burkholderia pseudomallei enoyl-acyl carrier protein reductase FabI1 is essential for in vivo growth and is the target of a novel chemotherapeutic with efficacy.Inefficient translation renders the Enterococcus faecalis fabK enoyl-acyl carrier protein reductase phenotypically crypticTriclosan - an update.Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 - 2010).
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Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im Januar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/01/18)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/18)
@nl
наукова стаття, опублікована в січні 2008
@uk
name
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@ast
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@en
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@nl
type
label
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@ast
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@en
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@nl
prefLabel
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@ast
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@en
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@nl
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P3181
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P1476
Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase
@en
P2093
John E. Cronan
R. Prisca Massengo-Tiassé
P2860
P304
P3181
P356
10.1074/JBC.M708171200
P407
P577
2008-01-18T00:00:00Z