Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan
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Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductaseType I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structureInhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamidesSlow-Onset Inhibition of the FabI Enoyl Reductase from Francisella tularensis : Residence Time and in Vivo ActivityA Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosisEffect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparumDetermination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzaeStructure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone InhibitorsRational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase InhibitorVibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductaseThe enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilisMechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia malleiDynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery.Determination of selectivity and efficacy of fatty acid synthesis inhibitors.Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosisPurification, characterization, and identification of novel inhibitors of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureusDefining and combating the mechanisms of triclosan resistance in clinical isolates of Staphylococcus aureus.Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum.Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomalleiIn silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitorsPotential impact of increased use of biocides in consumer products on prevalence of antibiotic resistanceGuideline for Hand Hygiene in Health-Care Settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force.Fatty acid biosynthesis as a target for novel antibacterialsA Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA'FAS't inhibition of malaria.Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase.Aqueous Molecular Dynamics Simulations of the M. tuberculosis Enoyl-ACP Reductase-NADH System and Its Complex with a Substrate Mimic or Diphenyl Ethers Inhibitors.Antimicrobial activity Study of triclosan-loaded WBPU on Proteus mirabilis in vitro.The Francisella tularensis FabI enoyl-acyl carrier protein reductase gene is essential to bacterial viability and is expressed during infection.Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coliPlasmid selection in Escherichia coli using an endogenous essential gene marker.Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.Do enthalpy and entropy distinguish first in class from best in class?Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.Substituted diphenyl ethers as a broad-spectrum platform for the development of chemotherapeutics for the treatment of tularaemiaResistance to AFN-1252 arises from missense mutations in Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI).Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.Structure and function of eukaryotic fatty acid synthases.Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds.Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.
P2860
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P2860
Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Kinetic and structural charact ...... rotein) reductase by triclosan
@ast
Kinetic and structural charact ...... rotein) reductase by triclosan
@en
Kinetic and structural charact ...... rotein) reductase by triclosan
@nl
type
label
Kinetic and structural charact ...... rotein) reductase by triclosan
@ast
Kinetic and structural charact ...... rotein) reductase by triclosan
@en
Kinetic and structural charact ...... rotein) reductase by triclosan
@nl
prefLabel
Kinetic and structural charact ...... rotein) reductase by triclosan
@ast
Kinetic and structural charact ...... rotein) reductase by triclosan
@en
Kinetic and structural charact ...... rotein) reductase by triclosan
@nl
P2093
P356
P1433
P1476
Kinetic and structural charact ...... rotein) reductase by triclosan
@en
P2093
C A Minshull
C J Britton
E G McLean
G A Holdgate
I W Taylor
P304
P356
10.1021/BI9907779
P407
P577
1999-09-21T00:00:00Z