Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds
about
Kinases as druggable targets in trypanosomatid protozoan parasitesDrug repurposing and human parasitic protozoan diseasesCorrection: Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical ScaffoldsIdentification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaignDiscovery of a Carbazole-Derived Lead Drug for Human African TrypanosomiasisNew chemical scaffolds for human african trypanosomiasis lead discovery from a screen of tyrosine kinase inhibitor drugsLapatinib combined with neoadjuvant paclitaxel-trastuzumab-based chemotherapy in patients with human epidermal growth factor receptor 2-positive breast cancer: A meta-analysis of randomized controlled trials.Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites.Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasisGlycogen Synthase Kinase 3β Promotes the Endocytosis of Transferrin in the African TrypanosomeNovel drug discovery for Chagas disease.Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases.Novel Effects of Lapatinib Revealed in the African Trypanosome by Using Hypothesis-Generating Proteomics and Chemical Biology Strategies.Activity of anti-cancer protein kinase inhibitors against Leishmania spp.AEE788 Inhibits Basal Body Assembly and Blocks DNA Replication in the African Trypanosome.Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.Development of Predictive QSAR Models of 4-Thiazolidinones Antitrypanosomal Activity using Modern Machine Learning Algorithms.Novel lead compounds in pre-clinical development against African sleeping sickness
P2860
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P2860
Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@ast
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@en
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@nl
type
label
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@ast
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@en
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@nl
prefLabel
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@ast
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@en
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Lapatinib-binding protein kina ...... se-directed chemical scaffolds
@en
P2093
Kojo Mensa-Wilmot
Ranjan Behera
Samiksha Katiyar
Sarah M Thomas
Yuko Ogata
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0056150
P407
P577
2013-01-01T00:00:00Z