The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis
about
The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthasePotent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based designMechanistic insights from the crystal structures of a feast/famine regulatory protein from Mycobacterium tuberculosis H37RvX-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidisSynergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosisStructures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit MechanismPrioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosisDifferential producibility analysis (DPA) of transcriptomic data with metabolic networks: deconstructing the metabolic response of M. tuberculosisPurified recombinant hypothetical protein coded by open reading frame Rv1885c of Mycobacterium tuberculosis exhibits a monofunctional AroQ class of periplasmic chorismate mutase activityThe two chorismate mutases from both Mycobacterium tuberculosis and Mycobacterium smegmatis: biochemical analysis and limited regulation of promoter activity by aromatic amino acidsKinetic mechanism determination and analysis of metal requirement of dehydroquinate synthase from Mycobacterium tuberculosis H37Rv: an essential step in the function-based rational design of anti-TB drugspheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activityFunctional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purificationThe mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analysesUnravelling the Secrets of Mycobacterial Cidality through the Lens of AntisenseThe conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase.Insights on the evolution of metabolic networks of unicellular translationally biased organisms from transcriptomic data and sequence analysis.In vivo Himar1-based transposon mutagenesis of Francisella tularensis.Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements.Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori.A PubMed-wide associational study of infectious diseases.Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosisMultiple Substrate Usage of Coxiella burnetii to Feed a Bipartite Metabolic Network.Essential metabolites of Mycobacterium tuberculosis and their mimicsComplete genome sequence of the frog pathogen Mycobacterium ulcerans ecovar LiflandiiHierarchical virtual screening for the discovery of new molecular scaffolds in antibacterial hit identificationAttenuation and persistence of and ability to induce protective immunity to a Staphylococcus aureus aroA mutant in mice.Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials.The use of live attenuated bacteria as a delivery system for heterologous antigens.Screening of antitubercular compound library identifies novel shikimate kinase inhibitors of Mycobacterium tuberculosis.Crystal Structure of Mycobacterium tuberculosis H37Rv AldR (Rv2779c), a Regulator of the ald Gene: DNA BINDING AND IDENTIFICATION OF SMALL MOLECULE INHIBITORS.Crystallization and preliminary X-ray diffraction analysis of prephenate dehydratase from Mycobacterium tuberculosis H37Rv.Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of 3-dehydroquinate synthase, Xoo1243, from Xanthomonas oryzae pv. oryzaeDrugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.Antimicrobial activity of curcumin against Helicobacter pylori isolates from India and during infections in mice.Growth, virulence, and immunogenicity of Listeria monocytogenes aro mutantsRegulatory and pathogenesis roles of Mycobacterium Lrp/AsnC family transcriptional factors.Multifaceted roles of curcumin: two sides of a coin!Review of knowledge for rational design and identification of anti-tubercular compounds.New tuberculosis drug development: targeting the shikimate pathway.
P2860
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P2860
The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Oktober 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/10/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/01)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في أكتوبر 2002)
@ar
name
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@ast
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@en
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@nl
type
label
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@ast
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@en
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@nl
prefLabel
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@ast
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@en
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@nl
P3181
P1433
P1476
The common aromatic amino acid ...... in Mycobacterium tuberculosis
@en
P304
P3181
P356
10.1099/00221287-148-10-3069
P577
2002-10-01T00:00:00Z