Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
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The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitorThe mechanism of action of PA-824: Novel insights from transcriptional profilingEmerging Roles of Toxin-Antitoxin Modules in Bacterial PathogenesisFit for consumption: zebrafish as a model for tuberculosisAntituberculosis therapy for 2012 and beyondRedox homeostasis in mycobacteria: the key to tuberculosis control?Combination therapies for combating antimicrobial resistanceX-ray Structure of 4,4'-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14 -Demethylase (CYP51)Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-CycloserineStructural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13Structure-Guided Discovery of Phenyl-diketo Acids as Potent Inhibitors of M. tuberculosis Malate SynthaseStructure of the Mtb CarD/RNAP β-Lobes Complex Reveals the Molecular Basis of Interaction and Presents a Distinct DNA-Binding Domain for Mtb CarDLassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2Oral Manifestations of Tuberculosis: Step towards Early DiagnosisA Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazineLocation of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatmentS-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferasesCholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2TB Mobile: a mobile app for anti-tuberculosis molecules with known targetsCombining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosisAuranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasisExpanding the pleuromutilin class of antibiotics by de novo chemical synthesis[Better search strategies, hopeful candidates. The search for new antimycobacterial drugs].Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32Compounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1).Discovery, synthesis, and biological evaluation of piperidinol analogs with anti-tuberculosis activity.Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis.Dry powder PA-824 aerosols for treatment of tuberculosis in guinea pigs.Activity of drug combinations against dormant Mycobacterium tuberculosisThe structure-activity relationship of urea derivatives as anti-tuberculosis agents.Essential metabolites of Mycobacterium tuberculosis and their mimicsFunctional characterization of EngA(MS), a P-loop GTPase of Mycobacterium smegmatis.Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey.Novel imidazoline antimicrobial scaffold that inhibits DNA replication with activity against mycobacteria and drug resistant Gram-positive cocciBayesian models leveraging bioactivity and cytotoxicity information for drug discovery.Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents.Depletion of antibiotic targets has widely varying effects on growthDrug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism.Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity
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Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@en
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@nl
type
label
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@en
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@nl
prefLabel
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@en
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@nl
P2093
P2860
P921
P356
P1476
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
@en
P2093
Eric J Rubin
James C Sacchettini
Joel S Freundlich
P2860
P2888
P356
10.1038/NRMICRO1816
P407
P577
2008-01-01T00:00:00Z
P6179
1044143694