A conserved dimer and global conformational changes in the structure of apo-PknE Ser/Thr protein kinase from Mycobacterium tuberculosis
about
Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA SplicingAuto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinaseAllosteric Activation Mechanism of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknBRv2969c, essential for optimal growth inMycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidasesThe crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformationEvidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosisUnderstanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase AProteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosisAllosteric activation by dimerization of the PknD receptor Ser/Thr protein kinase from Mycobacterium tuberculosisM. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homologMycobacterium tuberculosis protein kinase K enables growth adaptation through translation controlStructural effects of clinically observed mutations in JAK2 exons 13-15: comparison with V617F and exon 12 mutations.Mycobacterium tuberculosis Serine/Threonine Protein Kinases.Activation of PKR: an open and shut case?Key residues in Mycobacterium tuberculosis protein kinase G play a role in regulating kinase activity and survival in the host.Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases.Eukaryote-like serine/threonine kinases and phosphatases in bacteria.Bacterial cell division regulation by Ser/Thr kinases: a structural perspectiveRole of eukaryotic-like serine/threonine kinases in bacterial cell division and morphogenesis.The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.
P2860
Q27649529-18DDEFA3-1D50-4B5F-B44B-00A69505F51FQ27652901-3796D5B0-8C5E-45A7-B8E3-524EDA5DE8ACQ27666199-E5857E90-9940-4AFB-B397-15482088131AQ27680167-DD4284EB-9335-41DE-86A9-6A92AAEB0A70Q27697433-23CC0373-7BC4-4883-8A1B-9913DE5C45E6Q27697968-2C4910D3-3A3E-406D-A497-264E7EC1B05EQ28474053-02ED4CC5-BC61-4E9B-AAAE-3C588D29E6C1Q28479221-79A0E95D-876B-4858-8D8E-F52C0C927257Q28486430-06FB21B7-A64C-4FA1-945B-5E229C8B37CBQ28487585-B03E29E7-7968-4A45-B578-08ADC1738F6FQ28487634-A1020E5E-59AB-4149-ADB6-518224F0A704Q33501856-6DDB9B5F-6A97-40A8-8960-152F5C06355BQ34565203-0D592BC9-10D6-4C7E-8411-EF70A1D88368Q36695833-049B442C-2201-4245-B797-58F8E5F93FFEQ37448076-524DBA1C-F1FA-4BD6-A513-6208874D3BA3Q37633245-73AB5D48-83C6-4433-9F91-2C5CAC6A699DQ37849482-B83D6DC4-6EBA-4B48-B944-21AE4C7D602DQ38072994-2F10F498-8C36-483D-B27E-C83C77E1B620Q38597630-88E73985-0CA7-4237-A786-DA6E6FBBD843Q39038865-AF99042B-09E6-46C8-980B-BA823C824A5F
P2860
A conserved dimer and global conformational changes in the structure of apo-PknE Ser/Thr protein kinase from Mycobacterium tuberculosis
description
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Juli 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/07/07)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/07/07)
@nl
наукова стаття, опублікована в липні 2006
@uk
مقالة علمية (نشرت في 7-7-2006)
@ar
name
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@ast
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@en
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@nl
type
label
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@ast
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@en
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@nl
prefLabel
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@ast
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@en
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@nl
P2093
P1476
A conserved dimer and global c ...... rom Mycobacterium tuberculosis
@en
P2093
Ho-Leung Ng
Laurie M. Gay
P304
P356
10.1016/J.JMB.2006.05.015
P407
P577
2006-07-07T00:00:00Z