about
Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decaySatratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independentPKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulatorRegulation of PKR by HCV IRES RNA: importance of domain II and NS5AAnalysis of PKR activation using analytical ultracentrifugationImproved control of tuberculosis and activation of macrophages in mice lacking protein kinase RA Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.RNA structural elements of hepatitis C virus controlling viral RNA translation and the implications for viral pathogenesis.Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.Regulation of innate immunity through RNA structure and the protein kinase PKR.RNA helical imperfections regulate activation of the protein kinase PKR: effects of bulge position, size, and geometry.A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1Structural analysis of adenovirus VAI RNA defines the mechanism of inhibition of PKR.The use of analytical sedimentation velocity to extract thermodynamic linkage.Potential role for snoRNAs in PKR activation during metabolic stressControl of Morphological Differentiation of Streptomyces coelicolor A3(2) by Phosphorylation of MreC and PBP2Stress granules regulate double-stranded RNA-dependent protein kinase activation through a complex containing G3BP1 and Caprin1.Heparin activates PKR by inducing dimerization.Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective.Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT.The Regulatory and Kinase Domains but Not the Interdomain Linker Determine Human Double-stranded RNA-activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAsPromiscuous 8-alkoxyadenosines in the guide strand of an siRNA: modulation of silencing efficacy and off-pathway protein binding.Analysis of high-affinity binding of protein kinase R to double-stranded RNAEditing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress ResponsesMechanism of PKR Activation by dsRNA.PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cellsActivation of PKR by short stem-loop RNAs containing single-stranded arms.Staufen1 promotes HCV replication by inhibiting protein kinase R and transporting viral RNA to the site of translation and replication in the cells.RNA Regulation of Lipotoxicity and Metabolic Stress.Analysis of PKR structure by small-angle scattering.Domain stabilities in protein kinase R (PKR): evidence for weak interdomain interactionsRNA dimerization promotes PKR dimerization and activation.Activation of protein kinase PKR requires dimerization-induced cis-phosphorylation within the activation loop.Domain interactions in adenovirus VAI RNA mediate high-affinity PKR binding.Eukaryote-like serine/threonine kinases and phosphatases in bacteria.Activation of the Antiviral Kinase PKR and Viral Countermeasures.Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs.Analysis of PKR-RNA interactions by sedimentation velocityActivation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Activation of PKR: an open and shut case?
@ast
Activation of PKR: an open and shut case?
@en
type
label
Activation of PKR: an open and shut case?
@ast
Activation of PKR: an open and shut case?
@en
prefLabel
Activation of PKR: an open and shut case?
@ast
Activation of PKR: an open and shut case?
@en
P2860
P1476
Activation of PKR: an open and shut case?
@en
P2093
James L Cole
P2860
P356
10.1016/J.TIBS.2006.12.003
P577
2006-12-29T00:00:00Z