The Mycobacterium tuberculosis pks2 gene encodes the synthase for the hepta- and octamethyl-branched fatty acids required for sulfolipid synthesis
about
Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels developmentThe complete genome sequence of Mycobacterium avium subspecies paratuberculosisSulfite reduction in mycobacteriaEvolutionary landscape of the Mycobacterium tuberculosis complex from the viewpoint of PhoPR: implications for virulence regulation and application to vaccine developmentCrystal Structure of Mycobacterium tuberculosis Polyketide Synthase 11 (PKS11) Reveals Intermediates in the Synthesis of Methyl-branched AlkylpyronesMycocerosic acid synthase exemplifies the architecture of reducing polyketide synthasesRole of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameInduction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in cultureIdentification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screeningThe Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesisThe virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosisA sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosisHigh content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodelingPapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosisDisruption of msl3 abolishes the synthesis of mycolipanoic and mycolipenic acids required for polyacyltrehalose synthesis in Mycobacterium tuberculosis H37Rv and causes cell aggregationAttenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesisPhosphorylation of PhoP protein plays direct regulatory role in lipid biosynthesis of Mycobacterium tuberculosisIdentification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesisMycobacterial polyketide-associated proteins are acyltransferases: proof of principle with Mycobacterium tuberculosis PapA5Biochemical function of msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv: biosynthesis of monomethyl branched unsaturated fatty acidsA novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosisThe role of MmpL8 in sulfatide biogenesis and virulence of Mycobacterium tuberculosisIdentification of a diacylglycerol acyltransferase gene involved in accumulation of triacylglycerol in Mycobacterium tuberculosis under stressMmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulenceThe largest open reading frame (pks12) in the Mycobacterium tuberculosis genome is involved in pathogenesis and dimycocerosyl phthiocerol synthesis.Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survivalContribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistanceDeciphering sulfoglycolipids of Mycobacterium tuberculosis.Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.Slow growth of Mycobacterium tuberculosis at acidic pH is regulated by phoPR and host-associated carbon sources.Microbial type I fatty acid synthases (FAS): major players in a network of cellular FAS systems.Identification of DNA binding motifs of the Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system.The cell envelope glycoconjugates of Mycobacterium tuberculosisWax ester synthesis is required for Mycobacterium tuberculosis to enter in vitro dormancy.Transcription of genes involved in sulfolipid and polyacyltrehalose biosynthesis of Mycobacterium tuberculosis in experimental latent tuberculosis infection.Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis.Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigsMycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis
P2860
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P2860
The Mycobacterium tuberculosis pks2 gene encodes the synthase for the hepta- and octamethyl-branched fatty acids required for sulfolipid synthesis
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/18)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/18)
@nl
наукова стаття, опублікована в травні 2001
@uk
name
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@ast
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@en
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@nl
type
label
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@ast
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@en
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@nl
prefLabel
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@ast
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@en
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@nl
P2093
P2860
P3181
P356
P1476
The Mycobacterium tuberculosis ...... uired for sulfolipid synthesis
@en
P2093
A. K. Thirumala
H. Sprecher
P. E. Kolattukudy
T. D. Sirakova
V. S. Dubey
P2860
P304
16833–16839
P3181
P356
10.1074/JBC.M011468200
P407
P577
2001-05-18T00:00:00Z