Characterization of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 ORFs and mutants with altered virulence
about
Genomic-scale prioritization of drug targets: the TDR Targets databaseBiosynthesis and functions of mycothiol, the unique protective thiol of ActinobacteriaMycobacterial mutants with defective control of phagosomal acidificationThe trans-kingdom identification of negative regulators of pathogen hypervirulenceStructure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generationTranscriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosisInvestigating the function of the putative mycolic acid methyltransferase UmaA: divergence between the Mycobacterium smegmatis and Mycobacterium tuberculosis proteinsTrans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulenceThe Mycobacterium tuberculosis ino1 gene is essential for growth and virulenceCharacterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeatsDeletion of the Mycobacterium tuberculosis alpha-crystallin-like hspX gene causes increased bacterial growth in vivoInhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugsThe essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2Function of heterologous Mycobacterium tuberculosis InhA, a type 2 fatty acid synthase enzyme involved in extending C20 fatty acids to C60-to-C90 mycolic acids, during de novo lipoic acid synthesis in Saccharomyces cerevisiaeTranscriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal EnvironmentInactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37RvTB Mobile: a mobile app for anti-tuberculosis molecules with known targetsCombining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosisMicrosatellite polymorphism across the M. tuberculosis and M. bovis genomes: implications on genome evolution and plasticityIdentification of novel virulence determinants in Mycobacterium paratuberculosis by screening a library of insertional mutants.Generation and screening of a comprehensive Mycobacterium avium subsp. paratuberculosis transposon mutant bank.From Corynebacterium glutamicum to Mycobacterium tuberculosis--towards transfers of gene regulatory networks and integrated data analyses with MycoRegNet.Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.Characterization of novel Mycobacterium tuberculosis and Mycobacterium smegmatis mutants hypersusceptible to beta-lactam antibiotics.Using a label-free proteomics method to identify differentially abundant proteins in closely related hypo- and hypervirulent clinical Mycobacterium tuberculosis Beijing isolates.Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria.High throughput phenotypic selection of Mycobacterium tuberculosis mutants with impaired resistance to reactive oxygen species identifies genes important for intracellular growth.Exploring drug action on Mycobacterium tuberculosis using affymetrix oligonucleotide genechips.Drug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.Fatty acyl chains of Mycobacterium marinum lipooligosaccharides: structure, localization and acylation by PapA4 (MMAR_2343) proteinLipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells.Characterization of genome-wide ordered sequence-tagged Mycobacterium mutant libraries by Cartesian Pooling-Coordinate SequencingThe tuberculosis drug discovery and development pipeline and emerging drug targets.Role of intragenic binding of cAMP responsive protein (CRP) in regulation of the succinate dehydrogenase genes Rv0249c-Rv0247c in TB complex mycobacteriaAnalysis of IS6110 insertion sites provide a glimpse into genome evolution of Mycobacterium tuberculosis.Genomic epidemiology of Lineage 4 Mycobacterium tuberculosis subpopulations in New York City and New Jersey, 1999-2009.An expanded transposon-mutant library reveals that Vibrio fischeri δ-aminolevulinate auxotrophs can colonize Euprymna scolopesThe primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissueRibonucleotide reduction in Mycobacterium tuberculosis: function and expression of genes encoding class Ib and class II ribonucleotide reductases
P2860
Q24635333-7E8BC2B5-7B6F-4C06-A3A7-177A4293A7DFQ24646505-C8611623-2FAA-4973-BA07-112DD2CBAAB1Q24811622-ED60BFCE-E052-4493-B5BF-E259D8D9368DQ26782915-67861D89-5FEC-4444-839C-F346546F3282Q27688947-0C115790-4902-4C69-A3CD-03B08352FF93Q28469237-81940FE3-7DC0-4EE2-A016-2BFBE41FF47CQ28486588-923B51A2-43A0-423F-94C7-B0C4F1DFF215Q28486653-86E40C6E-7707-4008-8B0E-52FBB8D0651FQ28486746-8AA325DC-0799-4885-AE9A-F718D5E0CD66Q28486890-93A08B49-0C2C-4DCA-9CCA-4CB4A88C4D94Q28487051-960EF668-9FEE-4EF3-BDD9-CC7993925EAEQ28487121-47BCAB43-5044-4CBA-8057-457F9D7F15B6Q28487203-453963EF-FD42-46C7-A68C-9A7F3C0F91C4Q28487264-39114F05-1BED-4DF8-93BD-73A54F8F348FQ28487339-E32289D9-4A03-41A2-8AB9-1CD07F33EB5CQ28487447-4FD6B9A3-21F3-4C41-B8E4-F8555657AFC5Q28709353-531F86AD-96C7-4569-A9DC-ACB507E5CA28Q28709665-F7A06918-4A87-4410-B7D8-3E3E974B86FDQ28768438-85F38C6F-6014-4DF3-8D8E-FDDB3C17337AQ33247524-D1DD7D55-A92D-4CBB-BFD2-2A478C1EDF95Q33456925-91A0163F-0FFF-47C2-A7FF-D112D479F2EFQ33459692-EA52957D-A568-4215-8FAD-10B8E86CA077Q33476065-8FB8CC1D-794E-47B7-AB72-F64C69312381Q33714602-2344550C-4F1F-4340-AB9B-B16C12CB4FCEQ34320734-BC1D516E-D55F-4A3A-88E4-1E56A7BE5B7FQ34383371-1B59372F-7596-4D4F-80CB-1C38593108D3Q34548268-F1E633A7-0F84-4044-B1DE-3635481658C1Q35012666-79FA288C-771B-4DD3-A236-A2BCB0DC7BD3Q35020400-E004D8F3-8B2D-4E23-819C-5A041D400114Q35095367-B03564CB-E605-4B21-B65C-60BDFAFB24AFQ35312001-1757F669-FEF8-46D1-ADDF-F667D5C2BAC4Q35588375-8628A687-10CA-4915-A2EA-E64200EFCF9FQ35626469-B114CA35-98E3-4201-8A86-FCBB82C0E687Q35664209-70548A69-C4E9-4DB4-8CAB-EE1D7C0511ACQ35770624-BAAB3F53-C314-4C17-9D20-B5977C69CE51Q35895386-781B0D1E-0DE8-4E46-9CDB-FB49ACCD0459Q36199999-8F9C65B8-4246-4A93-AA69-28528CB67BFFQ36230782-F762FA76-122F-4394-A676-1C1A742FEBE3Q36350501-BB59BB0E-AF60-4338-B57F-CEBD90659E80Q36375500-8D20387B-AEDE-48ED-9044-315C116A5C58
P2860
Characterization of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 ORFs and mutants with altered virulence
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Oktober 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/10/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/01)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في أكتوبر 2002)
@ar
name
Characterization of a Mycobact ...... mutants with altered virulence
@ast
Characterization of a Mycobact ...... mutants with altered virulence
@en
Characterization of a Mycobact ...... mutants with altered virulence
@nl
type
label
Characterization of a Mycobact ...... mutants with altered virulence
@ast
Characterization of a Mycobact ...... mutants with altered virulence
@en
Characterization of a Mycobact ...... mutants with altered virulence
@nl
prefLabel
Characterization of a Mycobact ...... mutants with altered virulence
@ast
Characterization of a Mycobact ...... mutants with altered virulence
@en
Characterization of a Mycobact ...... mutants with altered virulence
@nl
P2093
P921
P1433
P1476
Characterization of a Mycobact ...... mutants with altered virulence
@en
P2093
Alan P. Lewis
Debbie A. Smith
Elizabeth U. Hooker
Fiona C. Cook
Gregory J. Bancroft
Joanna C. Betts
Ken Duncan
Martin J. Everett
Pauline T. Lukey
Peter Woollard
P304
P356
10.1099/00221287-148-10-2975
P577
2002-10-01T00:00:00Z