Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
about
Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cellsThe ornithine decarboxylase gene is essential for cell survival during early murine developmentTargeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesisInvolvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in DrosophilaChromosomal instability and lack of cyclin E regulation in hCdc4 mutant human breast cancer cellsAnalysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissuesGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesA role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell linesHuman F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell lineMultiple functions of FADD in apoptosis, NF-κB-related signaling, and heart development in Xenopus embryosMultiple functions of Jab1 are required for early embryonic development and growth potential in miceConstitutive turnover of cyclin E by Cul3 maintains quiescenceTargeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplicationTargeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethalityDisruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic deathThe NEDD8 system is essential for cell cycle progression and morphogenetic pathway in miceCUL-4A is critical for early embryonic developmentA Regulatory miRNA-mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney InjuryRegulation of the G1 to S transition by the ubiquitin pathway.Genes preferentially expressed in bovine oocytes revealed by subtractive and suppressive hybridization.A complex regulatory network coordinating cell cycles during C. elegans development is revealed by a genome-wide RNAi screen.Age-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American grey short-tailed opossum)Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis.Nedd8 on cullin: building an expressway to protein destruction.The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells.In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signalingUbiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators.Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.In vivo interference with Skp1 function leads to genetic instability and neoplastic transformationCullins and cancer.Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosomeMyc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.Oncogenic aberrations of cullin-dependent ubiquitin ligases.Molecular characterization of pancreatic serous microcystic adenomas: evidence for a tumor suppressor gene on chromosome 10q.Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.High-Throughput Profiling of Caenorhabditis elegans Starvation-Responsive microRNAs.Characterization of SCF-Complex during Bovine Preimplantation Developmentmir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans.
P2860
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P2860
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
description
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 1999
@ast
im Oktober 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/10/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/10/01)
@nl
наукова стаття, опублікована в жовтні 1999
@uk
name
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@ast
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@en
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@nl
type
label
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@ast
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@en
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@nl
prefLabel
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@ast
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@en
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@nl
P2093
P3181
P356
P1433
P1476
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
@en
P2093
Gstaiger M
Kipreos ET
P2888
P304
P3181
P356
10.1038/13886
P407
P577
1999-10-01T00:00:00Z