Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
about
BRCA1 affects global DNA methylation through regulation of DNMT1FGF-10 and its receptor exhibit bidirectional paracrine targeting to urothelial and smooth muscle cells in the lower urinary tractReceptor specificity of the fibroblast growth factor family. The complete mammalian FGF familyFrom fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung developmentEpithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compoundsP63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndromeSox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewalFgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung developmentReciprocal epithelial-mesenchymal FGF signaling is required for cecal developmentComparative molecular developmental aspects of the mammalian- and the avian lungs, and the insectan tracheal system by branching morphogenesis: recent advances and future directionsCellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.The dual roles of geminin during trophoblast proliferation and differentiationCytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis.Role of FGFR2-signaling in the pathogenesis of acne.Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2.Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation.Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid bodyMultiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.Transcriptional programs controlling perinatal lung maturationMutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome.Three-dimensional culture and FGF signaling drive differentiation of murine pluripotent cells to distal lung epithelial cells.The three R's of lung health and disease: repair, remodeling, and regeneration.A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes.Epithelial mesenchymal interactions, the ECM and limb development.Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development.A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia.Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assemblyConditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung.Interactions between NF-κB and SP3 connect inflammatory signaling with reduced FGF-10 expression.Fibroblast growth factors, old kids on the new block.The apical ectodermal ridge is a timer for generating distal limb progenitors.Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitorsIntegrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genesSignaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2.Patterning and plasticity in development of the respiratory lineage.Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT).The Fgfr2 W290R mouse model of Crouzon syndrome.Methylation of the FGFR2 gene is associated with high birth weight centile in humans.Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development.A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome.
P2860
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P2860
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
description
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1999
@ast
im Oktober 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/10/12)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/10/12)
@nl
наукова стаття, опублікована в жовтні 1999
@uk
name
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@ast
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@en
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@nl
type
label
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@ast
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@en
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@nl
prefLabel
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@ast
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@en
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@nl
P2093
P2860
P356
P1476
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis
@en
P2093
M. Gorivodsky
R. Haffner-Krausz
P2860
P304
11895–11899
P356
10.1073/PNAS.96.21.11895
P407
P577
1999-10-12T00:00:00Z