Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
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Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fateAnatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryoReprogramming cells with synthetic proteinsEx uno plures: molecular designs for embryonic pluripotencyCell lineage allocation within the inner cell mass of the mouse blastocystTroika of the mouse blastocyst: lineage segregation and stem cellsIntercellular interactions, position, and polarity in establishing blastocyst cell lineages and embryonic axesGutsy moves in mice: cellular and molecular dynamics of endoderm morphogenesisThe ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specificationSingle cells get together: High-resolution approaches to study the dynamics of early mouse developmentMolecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency networkSymmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cellsOrigin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo.The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation developmentOct4 kinetics predict cell lineage patterning in the early mammalian embryoOSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem CellsCo-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cellsInduction of Pluripotency in Mouse Somatic Cells with Lineage SpecifiersSequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates.Protein kinase C mediated extraembryonic endoderm differentiation of human embryonic stem cells.Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse.Charting Brachyury-mediated developmental pathways during early mouse embryogenesis.Models of global gene expression define major domains of cell type and tissue identitySulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cellsKetamine exposure in early development impairs specification of the primary germ cell layers.SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34+ Progenitor Cells.Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocysthmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip dataGATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.Efficient and directive generation of two distinct endoderm lineages from human ESCs and iPSCs by differentiation stage-specific SOX17 transduction.All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators.Epigenetic modifications in pluripotent and differentiated cells.Antibody-directed lentiviral gene transduction for live-cell monitoring and selection of human iPS and hES cells.Embryonic stem cell potency fluctuates with endogenous retrovirus activity.Klf5 regulates lineage formation in the pre-implantation mouse embryo.Probing the role of stochasticity in a model of the embryonic stem cell: heterogeneous gene expression and reprogramming efficiency.HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.
P2860
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P248
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P2860
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
description
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Februar 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/02/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/02/01)
@nl
наукова стаття, опублікована в лютому 2010
@uk
مقالة علمية (نشرت في فبراير 2010)
@ar
name
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@ast
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@en
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@nl
type
label
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@ast
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@en
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@nl
prefLabel
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@ast
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@en
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Sox17 promotes differentiation ...... ctly antagonizing self-renewal
@en
P2093
Alice E. Chen
Andrew P. McMahon
Douglas A. Melton
Hongkai Ji
John T. Dimos
Kathy K. Niakan
Kevin Eggan
Kit T. Rodolfa
Mariko Yamaki
René Maehr
P2860
P304
P3181
P356
10.1101/GAD.1833510
P577
2010-02-01T00:00:00Z