A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma
about
The tuberous sclerosis complexmTOR signaling in tumorigenesisGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberinSimulated space radiation-induced mutants in the mouse kidney display widespread genomic changeAnimal models of lymphangioleiomyomatosis (LAM) and tuberous sclerosis complex (TSC).Rheb is essential for murine developmentDeficiency in pulmonary surfactant proteins in mice with fatty acid binding protein 4-Cre-mediated knockout of the tuberous sclerosis complex 1 gene.Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.Modulation of cell migration and invasiveness by tumor suppressor TSC2 in lymphangioleiomyomatosis.Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 allelesCombination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2+/- Mice Is Superior to Everolimus Alone.Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue.Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.A brain proteomic investigation of rapamycin effects in the Tsc1+/- mouse model.Assessment of Response of Kidney Tumors to Rapamycin and Atorvastatin in Tsc1+/- Mice.A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules.Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock.Pml represses tumour progression through inhibition of mTOR.Treatment option(s) for pulmonary lymphangioleiomyomatosis: progress and current challenges.Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.Distinctive morphology of renal cell carcinomas in tuberous sclerosis.Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.Notch transactivates Rheb to maintain the multipotency of TSC-null cells.Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.
P2860
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P2860
A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma
description
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Juli 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/07/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/07/01)
@nl
наукова стаття, опублікована в липні 2005
@uk
مقالة علمية (نشرت في يوليو 2005)
@ar
name
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@ast
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@en
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@nl
type
label
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@ast
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@en
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@nl
prefLabel
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@ast
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@en
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@nl
P2093
P2860
P356
P1476
A mouse model of tuberous scle ...... etastatic renal cell carcinoma
@en
P2093
Andrew J H Smith
Catherine Wilson
David F R Griffiths
Edward Lazda
Jeremy P Cheadle
Julian R Sampson
Shelley Idziaszczyk
P2860
P304
P356
10.1093/HMG/DDI190
P577
2005-05-11T00:00:00Z