Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation-dependent expression
about
CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factorCidea is associated with lipid droplets and insulin sensitivity in humansMolecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector familyDual promoters control the cell-specific expression of the human cell death-inducing DFF45-like effector B geneCpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 bindingMolecular cloning and characterization of human caspase-activated DNaseUp-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient miceMolecular evolution of Cide family proteins: novel domain formation in early vertebrates and the subsequent divergenceDe-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis.Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alphaCIDE gene expression in adipose tissue, liver, and skeletal muscle from obese and lean pigsRNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27.Genome-wide analysis of molecular changes in IL-12-induced control of mammary carcinoma via IFN-gamma-independent mechanismsRegulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes.Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory responseTranscriptional activation of Fsp27 by the liver-enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis.CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis.CIDE-A is expressed in liver of old mice and in type 2 diabetic mouse liver exhibiting steatosisChronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis.Purification, crystallization and preliminary X-ray crystallographic analysis of the CIDE-N domain of Fsp27Tumor necrosis factor-induced c-myc expression in the absence of mitogenesis is associated with inhibition of adipocyte differentiation.Fat-specific protein 27 regulates storage of triacylglycerolFSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.Lipid droplets: FSP27 knockout enhances their sizzleHepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver.Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes.Role of glycoprotein 78 and cidec in hepatic steatosisAlcohol and fat promote steatohepatitis: a critical role for fat-specific protein 27/CIDEC.Fasting regulates FSP27 expression in the liverA functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEAIdentification of a novel integral plasma membrane protein induced during adipocyte differentiation.Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis.Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate.
P2860
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P2860
Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation-dependent expression
description
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1992
@ast
im April 1992 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1992/04/05)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/04/05)
@nl
наукова стаття, опублікована у квітні 1992
@uk
name
Cloning and transcriptional re ...... entiation-dependent expression
@ast
Cloning and transcriptional re ...... entiation-dependent expression
@en
Cloning and transcriptional re ...... entiation-dependent expression
@nl
type
label
Cloning and transcriptional re ...... entiation-dependent expression
@ast
Cloning and transcriptional re ...... entiation-dependent expression
@en
Cloning and transcriptional re ...... entiation-dependent expression
@nl
prefLabel
Cloning and transcriptional re ...... entiation-dependent expression
@ast
Cloning and transcriptional re ...... entiation-dependent expression
@en
Cloning and transcriptional re ...... entiation-dependent expression
@nl
P2093
P3181
P1476
Cloning and transcriptional re ...... entiation-dependent expression
@en
P2093
G. M. Ringold
U. Danesch
P304
P3181
P407
P577
1992-04-05T00:00:00Z