Instability of Hes7 protein is crucial for the somite segmentation clock
about
From dynamic expression patterns to boundary formation in the presomitic mesodermNumber of active transcription factor binding sites is essential for the Hes7 oscillator.A model for generating circadian rhythm by coupling ultradian oscillators.A proposed mechanism for the interaction of the segmentation clock and the determination front in somitogenesisFast synchronization of ultradian oscillators controlled by delta-notch signaling with cis-inhibition.Control of Hes7 expression by Tbx6, the Wnt pathway and the chemical Gsk3 inhibitor LiCl in the mouse segmentation clockDelta-Notch signalling in segmentationTopology and dynamics of the zebrafish segmentation clock core circuitThe period of the somite segmentation clock is sensitive to Notch activityDelta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell systemNotch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somitesThe canonical Notch signaling pathway: unfolding the activation mechanism.Notch signalling: a simple pathway becomes complexReal-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells.Random cell movement promotes synchronization of the segmentation clockSingle-cell-resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamicsDifferential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.Complex dynamics of transcription regulation.Dynamical principles of two-component genetic oscillators.Setting the tempo in development: an investigation of the zebrafish somite clock mechanismModeling the zebrafish segmentation clock's gene regulatory network constrained by expression data suggests evolutionary transitions between oscillating and nonoscillating transcriptionZebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites.MiR-206-mediated dynamic mechanism of the mammalian circadian clockReduction theories elucidate the origins of complex biological rhythms generated by interacting delay-induced oscillations.Hes7 3'UTR is required for somite segmentation functionUltradian oscillations and pulses: coordinating cellular responses and cell fate decisionsScoliosis and segmentation defects of the vertebrae.Intrinsically disordered segments affect protein half-life in the cell and during evolution.Noise-resistant and synchronized oscillation of the segmentation clock.Whole Genome Sequencing Identifies a Missense Mutation in HES7 Associated with Short Tails in Asian Domestic CatsIntronic delay is essential for oscillatory expression in the segmentation clockNoncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.Canine disorder mirrors human disease: exonic deletion in HES7 causes autosomal recessive spondylocostal dysostosis in miniature Schnauzer dogs.Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia.Models in biology: 'accurate descriptions of our pathetic thinking'.Modelling coupled oscillations in the Notch, Wnt, and FGF signaling pathways during somitogenesis: a comprehensive mathematical model.JAK/Stat signaling regulates heart precursor diversification in DrosophilaThe Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub.The synchrony and cyclicity of developmental eventsUltradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
P2860
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P2860
Instability of Hes7 protein is crucial for the somite segmentation clock
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/01)
@nl
наукова стаття, опублікована в липні 2004
@uk
name
Instability of Hes7 protein is crucial for the somite segmentation clock
@ast
Instability of Hes7 protein is crucial for the somite segmentation clock
@en
Instability of Hes7 protein is crucial for the somite segmentation clock
@nl
type
label
Instability of Hes7 protein is crucial for the somite segmentation clock
@ast
Instability of Hes7 protein is crucial for the somite segmentation clock
@en
Instability of Hes7 protein is crucial for the somite segmentation clock
@nl
prefLabel
Instability of Hes7 protein is crucial for the somite segmentation clock
@ast
Instability of Hes7 protein is crucial for the somite segmentation clock
@en
Instability of Hes7 protein is crucial for the somite segmentation clock
@nl
P2093
P2860
P3181
P356
P1433
P1476
Instability of Hes7 protein is crucial for the somite segmentation clock
@en
P2093
Hiromi Hirata
Hiroshi Kokubu
Julian Lewis
Ryoichiro Kageyama
Shuichi Yamada
Yasumasa Bessho
Yoshito Masamizu
P2860
P2888
P304
P3181
P356
10.1038/NG1372
P407
P577
2004-07-01T00:00:00Z
P5875
P6179
1031458908