Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
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The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cellsThe role of targeted protein degradation in early neural developmentEx uno plures: molecular designs for embryonic pluripotencyGrowth control mechanisms in neuronal regenerationA synthetic low-frequency mammalian oscillatorFrequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response.Complex dynamics of transcription regulation.MicroRNA-9 Modulates Hes1 ultradian oscillations by forming a double-negative feedback loop.Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.Burst BMP triggered receptor kinase activity drives Smad1 mediated long-term target gene oscillation in C2C12 cellsJAK/Stat signaling regulates heart precursor diversification in DrosophilaSerum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cellsFunction and mechanism of CNTF/LIF signaling in retinogenesisCircadian Clock Genes Are Essential for Normal Adult Neurogenesis, Differentiation, and Fate DeterminationMiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer CellsHES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cellsHes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotencyIntegrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways.Notch4-dependent antagonism of canonical TGF-β1 signaling defines unique temporal fluctuations of SMAD3 activity in sheared proximal tubular epithelial cells.Inhibition of protein synthesis alters protein degradation through activation of protein kinase B (AKT)Collective behavior in gene regulation: post-transcriptional regulation and the temporal compartmentalization of cellular cycles.Ultradian oscillators in somite segmentation and other biological events.Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.The role of dimerisation and nuclear transport in the Hes1 gene regulatory network.Experiments, measurements, and mathematical modeling to decipher time signals in development.Genetic visualization of notch signaling in mammalian neurogenesis.Interaction of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells.Dynamic expression and roles of Hes factors in neural development.Hes1: the maestro in neurogenesis.Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus.Hes-1 regulates the excitatory fate of neural progenitors through modulation of Tlx3 (HOX11L2) expression.BMP-induced REST regulates the establishment and maintenance of astrocytic identity.Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance.Unraveling the differential dynamics of developmental fate in central and peripheral nervous systems
P2860
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P2860
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@ast
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@en
type
label
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@ast
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@en
prefLabel
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@ast
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum.
@en
P2093
P2860
P356
P1476
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum
@en
P2093
Hiroki Nagahara
Ryoichiro Kageyama
Shigeki Yoshiura
Toshiyuki Ohtsuka
Yoshiko Takenaka
P2860
P304
11292-11297
P356
10.1073/PNAS.0701837104
P407
P577
2007-06-25T00:00:00Z