The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity
about
From dynamic expression patterns to boundary formation in the presomitic mesodermNotch promotes neural lineage entry by pluripotent embryonic stem cells.Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndromeLife rhythm as a symphony of oscillatory patterns: electromagnetic energy and sound vibration modulates gene expression for biological signaling and healing.α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in miceA multi-cell, multi-scale model of vertebrate segmentation and somite formationThe roles of Mesp family proteins: functional diversity and redundancy in differentiation of pluripotent stem cells and mammalian mesodermal developmentNotch signaling in human development and diseaseNotch signalling synchronizes the zebrafish segmentation clock but is not needed to create somite boundariesNotch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse developmentContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoThe period of the somite segmentation clock is sensitive to Notch activityRipply2 is essential for precise somite formation during mouse early developmentThe Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling programO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionTbx protein level critical for clock-mediated somite positioning is regulated through interaction between Tbx and RipplyO-fucosylation of DLL3 is required for its function during somitogenesisNotch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somitesPhenotypic models of evolution and development: geometry as destinyReal-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells.Ciona intestinalis as a model for cardiac development.Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm.Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.Setting the tempo in development: an investigation of the zebrafish somite clock mechanismExtensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation.Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesodermTiming embryo segmentation: dynamics and regulatory mechanisms of the vertebrate segmentation clock.Signaling gradients during paraxial mesoderm development.Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectivesNotch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.Transitions between epithelial and mesenchymal states and the morphogenesis of the early mouse embryo.Hes7 3'UTR is required for somite segmentation functionTbx6-mediated Notch signaling controls somite-specific Mesp2 expression.Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycleCircadian genes, xBmal1 and xNocturnin, modulate the timing and differentiation of somites in Xenopus laevisMBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension.The synchrony and cyclicity of developmental eventsDivergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
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The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity
description
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2005
@ast
scientific journal article
@en
vedecký článok (publikovaný 2005/05/19)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/05/19)
@nl
наукова стаття, опублікована в травні 2005
@uk
مقالة علمية (نشرت في 19-5-2005)
@ar
name
The Mesp2 transcription factor ...... by suppressing Notch activity
@ast
The Mesp2 transcription factor ...... by suppressing Notch activity
@en
The Mesp2 transcription factor ...... by suppressing Notch activity
@nl
type
label
The Mesp2 transcription factor ...... by suppressing Notch activity
@ast
The Mesp2 transcription factor ...... by suppressing Notch activity
@en
The Mesp2 transcription factor ...... by suppressing Notch activity
@nl
prefLabel
The Mesp2 transcription factor ...... by suppressing Notch activity
@ast
The Mesp2 transcription factor ...... by suppressing Notch activity
@en
The Mesp2 transcription factor ...... by suppressing Notch activity
@nl
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P2860
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The Mesp2 transcription factor ...... by suppressing Notch activity
@en
P2093
Mitsuru Morimoto
Yu Takahashi
Yumiko Saga
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P2888
P304
P3181
P356
10.1038/NATURE03591
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P577
2005-05-19T00:00:00Z
P5875
P6179
1028639570