SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter
about
Where is it and How Does it Get There - Intracellular Localization and Traffic of P-glycoproteinRole of the C terminus of the photoreceptor ABCA4 transporter in protein folding, function, and retinal degenerative diseases.Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology.Celecoxib-mediated activation of endoplasmic reticulum stress induces de novo ceramide biosynthesis and apoptosis in hepatoma HepG2 cells mobilization.Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexinOverexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1Intracellular trafficking of P-glycoprotein.Sphingomyelin in high-density lipoproteins: structural role and biological function.Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.ABC transporters, atherosclerosis and inflammation.Functional implications of sterol transport by the oxysterol-binding protein gene family.PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism.Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression.Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis.Intracellular and Plasma Membrane Events in Cholesterol Transport and Homeostasis
P2860
Q27008624-E33D6F7A-6DF5-465A-B3FB-D99B65A013CEQ30373731-A3C41F8C-874F-4612-AE58-F81C9F2BD642Q33568675-6CABFE00-B95F-487E-A7B4-7803744E46B9Q33649252-DFD37D48-5BDA-40DD-8A12-FE670E716CC3Q33855331-DCEF5268-DC14-40AD-AB31-F2135DCFD251Q34146122-2FEDF056-4DF5-4438-B12C-E6920ECF7EE9Q34355599-25354F48-8E36-45E0-B5BD-63FCA29F86BAQ35013547-C2525615-E7B3-4FE3-8683-1151DE28850BQ35784974-B1483BFF-0C84-4C5A-8358-23BBEE1B5BB5Q36820504-800C5880-3B62-4D2B-82AB-180126EE4FA5Q37375669-16A3709A-EA21-4556-88E6-6ED7CC0648EFQ37415663-A9548B54-32A0-4CA2-AC15-FAD426D71A72Q37688500-7159A76C-D02E-4901-B8D6-3A411B8EE3B9Q37764891-FDCFAEE7-767D-488F-84AE-4C167D1B36CEQ37895205-5695FBFC-1B9A-46E7-8141-0DF162CF452BQ39342347-84B5F5EC-EBAC-4F4A-99C1-D691231A9257Q47108131-1AA29FC9-F897-4E2D-AF11-A1038D97D4CCQ58798700-D797B03E-2BC5-439E-B603-8F4C577FBFB1
P2860
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter
description
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Juni 2008 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/06/10)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/06/10)
@nl
наукова стаття, опублікована в червні 2008
@uk
مقالة علمية (نشرت في 10-6-2008)
@ar
name
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@ast
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@en
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@nl
type
label
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@ast
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@en
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@nl
prefLabel
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@ast
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@en
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@nl
P2093
P2860
P356
P1433
P1476
SPTLC1 binds ABCA1 to negative ...... ux activity of the transporter
@en
P2093
Cari E. Brown
Debbie Z. Zhuang
Eicke Latz
Keiichiro Okuhira
Mason W. Freeman
Michael L. Fitzgerald
Norimasa Tamehiro
Ramnik J. Xavier
Suiping Zhou
Thorsten Hornemann
P2860
P304
P356
10.1021/BI800182T
P407
P577
2008-06-10T00:00:00Z