Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
about
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteinsALKBH4-dependent demethylation of actin regulates actomyosin dynamics.N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTODNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferationThe obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylaseHuman AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNAOxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTOCrystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNAHuman ALKBH7 is required for alkylation and oxidation-induced programmed necrosisRepair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNAA non-heme iron-mediated chemical demethylation in DNA and RNAVitamin C: update on physiology and pharmacologyAlleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkBCrystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition.A role for Saccharomyces cerevisiae Tpa1 protein in direct alkylation repairHuman ALKBH4 interacts with proteins associated with transcriptionImpaired placental trophoblast lineage differentiation in Alkbh1(-/-) miceNoncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolismBiological properties of single chemical-DNA adducts: a twenty year perspectiveIron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity.Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centersOncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological ConditionsTet-mediated formation of 5-hydroxymethylcytosine in RNA.Neuroproteomics: an insight into ALS.Screening for coding variants in FTO and SH2B1 genes in Chinese patients with obesity.X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2.Expression and sub-cellular localization of human ABH family molecules.Differential repair of etheno-DNA adducts by bacterial and human AlkB proteinsThe DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation.Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteinsAlkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts.What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.Viral AlkB proteins repair RNA damage by oxidative demethylationRoles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine LesionsFluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker.Bioinformatics and functional analysis define four distinct groups of AlkB DNA-dioxygenases in bacteria.Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.
P2860
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P2860
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
description
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2005
@ast
im November 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/11/25)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/11/25)
@nl
наукова стаття, опублікована в листопаді 2005
@uk
name
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@ast
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@en
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@nl
type
label
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@ast
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@en
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@nl
prefLabel
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@ast
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@en
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@nl
P2093
P2860
P921
P356
P1476
Repair of methylation damage in DNA and RNA by mammalian AlkB homologues
@en
P2093
Dong-Hyun Lee
Gerd P. Pfeifer
Seung-Gi Jin
Timothy R. O'Connor
P2860
P304
39448–39459
P356
10.1074/JBC.M509881200
P407
P577
2005-11-25T00:00:00Z