Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
about
Ubiquitin-proteasome system involvement in Huntington's diseaseMood disorders in Huntington's disease: from behavior to cellular and molecular mechanismsHuntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in AplysiaGenome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysisOligonucleotide therapeutic approaches for Huntington diseaseHuntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitorsComparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxiaHuntingtin promotes cell survival by preventing Pak2 cleavageHuntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 GluedMini- and microsatellitesLoss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse developmentMultiple Aspects of Gene Dysregulation in Huntington's DiseaseCongenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineagesHuman single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's diseaseCAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroupTransgenic models of Huntington's diseaseReversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregationInactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.Sumoylation in Synaptic Function and DysfunctionNeural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challengesThe many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapyHuntington's disease: the past, present, and future search for disease modifiers.Transgenic animal models for study of the pathogenesis of Huntington's disease and therapyModeling Huntington's disease with induced pluripotent stem cellsThe N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model.SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delaminationN17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic miceHDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophyHuntingtin's function in axonal transport is conserved in Drosophila melanogasterDeficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideumHuntingtin functions as a scaffold for selective macroautophagyExpression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin IIInhibition of axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion proteinDentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosisOpposing effects of polyglutamine expansion on native protein complexes contribute to SCA1Normal huntingtin function: an alternative approach to Huntington's diseaseStage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome geneGenetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesisCellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic miceDeletion of the triplet repeat encoding polyglutamine within the mouse Huntington's disease gene results in subtle behavioral/motor phenotypes in vivo and elevated levels of ATP with cellular senescence in vitro
P2860
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P2860
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
description
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 1995
@ast
im Oktober 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/10/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/10/01)
@nl
наукова стаття, опублікована в жовтні 1995
@uk
name
Increased apoptosis and early ...... ngton's disease gene homologue
@ast
Increased apoptosis and early ...... ngton's disease gene homologue
@en
Increased apoptosis and early ...... ngton's disease gene homologue
@nl
type
label
Increased apoptosis and early ...... ngton's disease gene homologue
@ast
Increased apoptosis and early ...... ngton's disease gene homologue
@en
Increased apoptosis and early ...... ngton's disease gene homologue
@nl
prefLabel
Increased apoptosis and early ...... ngton's disease gene homologue
@ast
Increased apoptosis and early ...... ngton's disease gene homologue
@en
Increased apoptosis and early ...... ngton's disease gene homologue
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Increased apoptosis and early ...... ngton's disease gene homologue
@en
P2093
A. Efstratiadis
D. L. Chapman
S. Zeitlin
P2860
P2888
P304
P3181
P356
10.1038/NG1095-155
P407
P577
1995-10-01T00:00:00Z
P6179
1035910928