Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye
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The bilaterian head patterning gene six3/6 controls aboral domain development in a cnidarianMutations in the human SIX3 gene in holoprosencephaly are loss of functionSox2 and Pou2f1 interact to control lens and olfactory placode developmentRepression of Six3 by a corepressor regulates rhodopsin expressionEfficient activation of gene expression using a heat-shock inducible Gal4/Vp16-UAS system in medakaComprehensive in silico functional specification of mouse retina transcriptsSix3 regulates optic nerve development via multiple mechanisms.Gene Expression Data from the Moon Jelly, Aurelia, Provide Insights into the Evolution of the Combinatorial Code Controlling Animal Sense Organ DevelopmentRegulation of a remote Shh forebrain enhancer by the Six3 homeoproteinDevelopment of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8Holoprosencephaly.Comparative analysis of gene expression for convergent evolution of camera eye between octopus and human.In vivo validation of a computationally predicted conserved Ath5 target gene setSIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fishSpatiotemporal features of neurogenesis in the retina of medaka, Oryzias latipesCerebroventricular microinjection (CVMI) into adult zebrafish brain is an efficient misexpression method for forebrain ventricular cells.Candidate gene screen in the red flour beetle Tribolium reveals six3 as ancient regulator of anterior median head and central complex development.Loss of eyes in zebrafish caused by mutation of chokh/rx3.Side chain modified peptide nucleic acids (PNA) for knock-down of six3 in medaka embryos.Uncoupling of complex regulatory patterning during evolution of larval development in echinoderms.Otx2 is involved in the regional specification of the developing retinal pigment epithelium by preventing the expression of sox2 and fgf8, factors that induce neural retina differentiation.Six3 demarcates the anterior-most developing brain region in bilaterian animals.Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in miceOntogenesis of peptidergic neurons within the genoarchitectonic map of the mouse hypothalamus.Nanosecond pulsed electric field suppresses development of eyes and germ cells through blocking synthesis of retinoic acid in Medaka (Oryzias latipes).Use of medaka in toxicity testing.Early steps in the development of the forebrainSignaling during lens regeneration.Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling.Eye evolution: common use and independent recruitment of genetic components.Regenerative therapy for retinal disorders.Ethanol alters gene expression and cell organization during optic vesicle evagination.A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3.FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro.Cavefish eye loss in response to an early block in retinal differentiation progression.Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expressionSix3 represses nodal activity to establish early brain asymmetry in zebrafish.Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain.
P2860
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P2860
Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye
description
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
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im September 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/09/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/09/01)
@nl
наукова стаття, опублікована у вересні 2002
@uk
مقالة علمية (نشرت في سبتمبر 2002)
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name
Six3 inactivation reveals its ...... tterning of the vertebrate eye
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Six3 inactivation reveals its ...... tterning of the vertebrate eye
@en
Six3 inactivation reveals its ...... tterning of the vertebrate eye
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type
label
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@ast
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@en
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@nl
prefLabel
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@ast
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@en
Six3 inactivation reveals its ...... tterning of the vertebrate eye
@nl
P2093
P1433
P1476
Six3 inactivation reveals its ...... tterning of the vertebrate eye
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P2093
Felix Loosli
Joachim Wittbrodt
Matthias Carl
P304
P407
P577
2002-09-01T00:00:00Z