Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
about
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOTThe human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation techniqueStructural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinThe interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targetsPhosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fateMammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationHuman Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodiesThe Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescenceNot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinCNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell deathPost-transcriptional Regulation of Genes Encoding Anti-microbial Peptides in DrosophilaWho Regulates Whom? An Overview of RNA Granules and Viral InfectionsEnterovirus Control of Translation and RNA Granule Stress ResponsesMechanisms of deadenylation-dependent decayReading RNA methylation codes through methyl-specific binding proteinsComposition and function of P bodies in Arabidopsis thalianaThe panorama of miRNA-mediated mechanisms in mammalian cellsHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexNutrients and the Pkh1/2 and Pkc1 protein kinases control mRNA decay and P-body assembly in yeastThe exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay PathwaysPhosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitmentNANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAsLarge G3BP-induced granules trigger eIF2α phosphorylation.hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.Poliovirus-mediated disruption of cytoplasmic processing bodiesInsights into the structure and architecture of the CCR4-NOT complexDeadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Proteasomal activity is required to initiate and to sustain translational activation of messenger RNA encoding the stem-loop-binding protein during meiotic maturation in mice.A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly.Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.To polyadenylate or to deadenylate: that is the question.The regulation of mRNA stability in mammalian cells: 2.0.Cytoplasmic mRNP granules at a glanceDifferential utilization of decapping enzymes in mammalian mRNA decay pathways.Differential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools.Re-capping the message.Relationship of GW/P-bodies with stress granules.
P2860
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P2860
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Juli 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/07/14)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/14)
@nl
наукова стаття, опублікована в липні 2008
@uk
مقالة علمية (نشرت في 14-7-2008)
@ar
name
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@ast
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@en
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@nl
type
label
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@ast
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@en
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@nl
prefLabel
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@ast
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@en
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@nl
P2093
P2860
P921
P3181
P356
P1476
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
@en
P2093
Ann-Bin Shyu
Chyi-Ying A Chen
Nader Ezzeddine
Wenmiao Zhu
Xiangwei He
P2860
P304
P3181
P356
10.1083/JCB.200801196
P407
P577
2008-07-01T00:00:00Z