Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
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PPAR(alpha) and PPAR(gamma) activators suppress the monocyte-macrophage apoB-48 receptorReduction of plasma triglycerides in apolipoprotein C-II transgenic mice overexpressing lipoprotein lipase in muscleType III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2Evidence for differential effects of apoE3 and apoE4 on HDL metabolismA plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cellsLXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytesDisruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient miceInducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnantsTwo Hsp70 family members expressed in atherosclerotic lesionsTargeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in miceGranzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout miceLow-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependentThe intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humansAn Update on the Use of Animal Models in Diabetic Nephropathy ResearchGlycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 and the intravascular processing of triglyceride-rich lipoproteinsHypoxia in murine atherosclerotic plaques and its adverse effects on macrophagesAnimal models of age related macular degenerationImaging of small animal peripheral artery disease models: recent advancements and translational potentialIn vitro models of aortic valve calcification: solidifying a systemAdaptive immunity and atherosclerosis: mouse tales in the AJPRegression of atherosclerosis: insights from animal and clinical studiesThe thyroid receptor modulator KB3495 reduces atherosclerosis independently of total cholesterol in the circulation in ApoE deficient miceGenetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred StrainsEpigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathwayElucidation of monocyte/macrophage dynamics and function by intravital imaging.Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammalsIdentification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type IZebrafish Models for Dyslipidemia and Atherosclerosis ResearchMolecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models.A macrophage receptor for apolipoprotein B48: cloning, expression, and atherosclerosisTANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulumRegulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and betaNormal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemiaAtherogenesis in perspective: hypercholesterolemia and inflammation as partners in crimeTheoretical and empirical issues for marker-assisted breeding of congenic mouse strainsA wax ester and astaxanthin-rich extract from the marine copepod Calanus finmarchicus attenuates atherogenesis in female apolipoprotein E-deficient miceInflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applicationsInhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout miceIncreased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin EDirect effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice
P2860
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P2860
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
description
1992 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1992
@ast
im Oktober 1992 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1992/10/16)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/10/16)
@nl
наукова стаття, опублікована в жовтні 1992
@uk
مقالة علمية (نشرت في 16-10-1992)
@ar
name
Severe hypercholesterolemia an ...... gous recombination in ES cells
@ast
Severe hypercholesterolemia an ...... gous recombination in ES cells
@en
Severe hypercholesterolemia an ...... gous recombination in ES cells
@nl
type
label
Severe hypercholesterolemia an ...... gous recombination in ES cells
@ast
Severe hypercholesterolemia an ...... gous recombination in ES cells
@en
Severe hypercholesterolemia an ...... gous recombination in ES cells
@nl
prefLabel
Severe hypercholesterolemia an ...... gous recombination in ES cells
@ast
Severe hypercholesterolemia an ...... gous recombination in ES cells
@en
Severe hypercholesterolemia an ...... gous recombination in ES cells
@nl
P2093
P921
P3181
P1433
P1476
Severe hypercholesterolemia an ...... gous recombination in ES cells
@en
P2093
A. S. Plump
E. M. Rubin
J. D. Smith
J. G. Verstuyft
J. L. Breslow
K. Aalto-Setälä
P304
P3181
P356
10.1016/0092-8674(92)90362-G
P407
P577
1992-10-16T00:00:00Z