LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes - Wikidata - wikimedia - TriplyDB

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

http://www.wikidata.org/entity/Q24548189

about

Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol Synthetic LXR ligand inhibits the development of atherosclerosis in mice Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein Potentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1 alpha Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1 24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue Establishment of a monoclonal antibody for human LXRalpha: Detection of LXRalpha protein expression in human macrophages Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport Crystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonism Crystal structure of the heterodimeric complex of LXR and RXR ligand-binding domains in a fully agonistic conformation Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways Liver X receptors at the intersection of lipid metabolism and atherogenesis Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism Cholesterol, inflammation and innate immunity Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors Identification of a peroxisome-proliferator-activated-receptor response element in the apolipoprotein E gene control region Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE Glucose regulates LXRalpha subcellular localization and function in rat pancreatic beta-cells Liver X receptors regulate cholesterol homeostasis in oligodendrocytes Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density lipoprotein Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target Non-redundant roles for LXRalpha and LXRbeta in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice.Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes Bifidobacteria can protect from enteropathogenic infection through production of acetate Liver X Receptors Link Lipid Metabolism and Inflammation.Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading Nuclear receptors as drug targets for metabolic disease.Tgif1 represses apolipoprotein gene expression in liver.

P2860

Q24291555-0282A736-ABEA-47A2-AEEA-33DAA101C684 Q24300591-D5EEF8D3-757E-444E-8835-3A63E125FF54 Q24312559-8F2B9515-8ABD-4AFE-B527-C0263A4F4664 Q24314471-73985BBD-DD63-4A1A-B96B-A8C080521CBB Q24317054-B3406305-5547-444E-9960-2F9004EF6DC7 Q24317341-C7865C4C-7310-44AA-85C3-E631CC272E64 Q24337296-2BC3C12B-7359-4711-A632-F631DCC5EB72 Q24337975-B579BA32-1024-413D-AC69-91223D94932E Q24530617-B7CAAAA2-9B73-4137-86C9-B364E2CDB5BD Q24535065-62885505-91D8-4370-9BC9-0A29C705AD48 Q24535642-48D51DE0-A21A-49C1-9313-E92DFB605CB0 Q24536348-B0EBA7BF-DD34-4E88-B419-19A50AF7EC1D Q24633440-663D3767-E97E-4CD7-9F43-1FA72391F018 Q24644336-E2FDBC82-44B5-4EFE-80A5-FC8515BD7399 Q24650450-4C493B17-FB86-4587-8E31-E8EA251C0AEC Q24674168-FD8EC0D5-CB0C-4216-AC5D-52131B1681E3 Q24677042-DD3C73B7-59B4-45E9-80AA-2C0688F902F0 Q24806573-52A2C271-585F-4581-AE3F-D22C3E271092 Q26866484-F68B1D0A-82CA-41DA-A117-27A7BAADADA2 Q27641100-D7ECE356-183D-4807-8153-23573AD6F274 Q27642012-B548E68F-4572-47F4-9489-1D5604009427 Q28081678-DAC62D76-D6AB-4384-A79A-83A42192EF0E Q28082452-E4CD990D-0C16-40D5-810C-30733EF36336 Q28084780-260FD74B-9870-4F19-BB86-4C440A8A4788 Q28086912-550BF305-DDE6-4E48-B029-215127B8FF42 Q28198291-5516964F-B905-4516-875F-9ED14A647092 Q28236615-DDB1B134-F78E-45CD-8CB6-C5912B9024AB Q28343603-66DD308C-D9D8-4596-98BB-CD22294DF8BF Q28513193-774960F6-A952-406F-9285-07C679A080B3 Q28579781-017F1154-134A-4FD6-AC61-4B95D6D7DCB3 Q28580791-B83B43E9-75FC-4D23-B88A-F6E526746B41 Q28585274-4609C0B5-AD10-4FCC-BC64-B042B1C238D5 Q28588828-D94FE20E-49E9-46AB-B89B-9DB86816048B Q28589168-094BB3D6-A498-4477-A217-22023A6FF324 Q28589822-9E60A3DE-14DE-4893-BE9E-C54B4C6BBF28 Q29617592-59DEF24B-2AD5-4DA3-86A6-E4173886AA76 Q30252316-9B53D4C4-150E-41D2-9019-69796D9366F1 Q30412216-C885C758-4348-4F96-93B6-7A40E261D534 Q30430126-521EB091-0FB1-4C3D-9621-E2AA38FE65C0 Q30430463-FDD525F4-332E-48F8-BF41-9B7AC93411FA

P2860

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

http://www.wikidata.org/entity/Q24548189

description

2001 nî lūn-bûn

@nan

2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@ast

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@en

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@nl

type

label

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@ast

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@en

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@nl

prefLabel

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@ast

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@en

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@nl

P1433

Q24548189-F9AF44C3-2E70-48A6-B367-7784EB008D97

P1476

Q24548189-3A7611F5-FED4-482C-97B4-CB13F53E9FFA

P2093

Q24548189-242412E2-21E3-4B8D-8DB9-B1B89BD6BAFE

Q24548189-28F9955D-4E56-4FCA-9119-9D6D8DF52F48

Q24548189-2917CC78-6E81-4611-9D37-E1D89C8EBE8B

Q24548189-32783803-5F41-4C3F-945D-A4486C74B67E

Q24548189-5D2DF016-57B8-4F04-B0DE-29075F6BA799

Q24548189-C22AE6C5-E4D4-4443-951E-6403D2BD90A5

Q24548189-E3A72FC4-390C-4D1C-AB25-E6050F8A2F2B

P2860

Q24548189-0A348143-78B4-46D2-85FA-0640266CDB49

Q24548189-1B7B997C-A20D-4AF3-ABB6-08962BDAD704

Q24548189-228F82A1-5E1B-4823-A255-4852F35C5438

Q24548189-290734D3-2EB0-4033-B684-8ABBEC635967

Q24548189-2DF7828B-83CE-483D-A910-F81443C11919

Q24548189-478CA094-4757-4BEF-90A2-3F277E27374B

Q24548189-4AE99B7C-45EC-4CC3-8320-8BA298035F97

Q24548189-5DE01B9C-5823-4B5A-BECF-83CE9251D656

Q24548189-6428FC18-A823-4872-8294-521F098FA21C

Q24548189-6F110D35-C9DA-482B-B9B2-FA84265DE4B6

P304

Q24548189-30A691A8-0D1A-43A2-8D99-A72B77AA3206

P31

Q24548189-A678A86D-24B1-43A4-B139-7BDAB0B02C19

P3181

Q24548189-B0D1931E-C331-451E-BC85-539B3E8A90EC

P356

Q24548189-7E53CBE6-9B02-438E-B14C-A38ABC0060BE

Q24548189-AD5249B6-9E2F-4B45-9BE2-46EC853EA50C

P407

Q24548189-2E29143A-E90D-4B62-AAF7-AD92E0AA7DCA

P433

Q24548189-CEF7935D-C3A2-4A2B-8143-54FF8438FBCF

P478

Q24548189-D60CCF28-66B7-4137-8B73-6759765CAF38

P577

Q24548189-78F15479-7525-4526-9C33-32504D1F07E0

P698

Q24548189-610D6AD9-5DA6-4EB7-9DF8-CCE5D2319F8A

P921

Q24548189-076CD319-DCC2-45F6-9191-790C340C8FD5

P932

Q24548189-82000533-8666-4135-946E-4F018CC624C5

P3181

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

LXRs control lipid-inducible e ...... in macrophages and adipocytes

@en

P2093

B A Laffitte

http://www.w3.org/2001/XMLSchema#string

D C Wilpitz

http://www.w3.org/2001/XMLSchema#string

D J Mangelsdorf

http://www.w3.org/2001/XMLSchema#string

H R Kast

http://www.w3.org/2001/XMLSchema#string

J J Repa

http://www.w3.org/2001/XMLSchema#string

P Tontonoz

http://www.w3.org/2001/XMLSchema#string

S B Joseph

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

LXR, a nuclear receptor that defines a distinct retinoid response pathway

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

P304

507-12

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1279871

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.021488798

http://www.w3.org/2001/XMLSchema#string

10.1073/PNAS.98.2.507

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

98

http://www.w3.org/2001/XMLSchema#string

P577

2001-01-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11149950

http://www.w3.org/2001/XMLSchema#string

P921

P932

14617

http://www.w3.org/2001/XMLSchema#string