A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages
about
Sp8 is crucial for limb outgrowth and neuropore closureGene regulatory networks in cardiac conduction system developmentThe Role of the Ubiquitously Expressed Transcription Factor Sp1 in Tissue-specific Transcriptional Regulation and in DiseaseInherited conduction system abnormalities--one group of diseases, many genesSpecificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblastsSp3 proteins negatively regulate beta myosin heavy chain gene expression during skeletal muscle inactivityTranscription of mouse Sp2 yields alternatively spliced and sub-genomic mRNAs in a tissue- and cell-type-specific fashionGenetic aspects of arrhythmias.Mixed signals in heart failure: cancer rules.Contactin-2 expression in the cardiac Purkinje fiber networkCardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden deathKnockout of the neural and heart expressed gene HF-1b results in apical deficits of ventricular structure and activationNotch signaling plays a key role in cardiac cell differentiation.Transcription factors Sp1 and Sp4 regulate TRPV1 gene expression in rat sensory neurons.Evaluation and applications of radiotelemetry in small laboratory animals.A decade of discoveries in cardiac biology.Transcription factor Sp4 regulates dendritic patterning during cerebellar maturationA novel subfamily of zinc finger genes involved in embryonic development.Complete heart block and sudden death in mice overexpressing calreticulin.Transcription factor Sp3 knockout mice display serious cardiac malformations.Irx3 is required for postnatal maturation of the mouse ventricular conduction systemNeural development is dependent on the function of specificity protein 2 in cell cycle progression.Visualization and functional characterization of the developing murine cardiac conduction system.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.Current insights into LMNA cardiomyopathies: Existing models and missing LINCsGenotype, phenotype: upstairs, downstairs in the family of cardiomyopathiesA mathematical model of action potential heterogeneity in adult rat left ventricular myocytes.Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes.Calcium-dependent arrhythmias in transgenic mice with heart failure.Development and Function of the Cardiac Conduction System in Health and Disease.Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant mice.Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization.Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice.A novel early onset lethal form of catecholaminergic polymorphic ventricular tachycardia maps to chromosome 7p14-p22
P2860
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P2860
A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages
description
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im September 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/09/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/09/01)
@nl
наукова стаття, опублікована у вересні 2000
@uk
مقالة علمية (نشرت في سبتمبر 2000)
@ar
name
A novel genetic pathway for su ...... onduction system cell lineages
@ast
A novel genetic pathway for su ...... onduction system cell lineages
@en
A novel genetic pathway for su ...... onduction system cell lineages
@nl
type
label
A novel genetic pathway for su ...... onduction system cell lineages
@ast
A novel genetic pathway for su ...... onduction system cell lineages
@en
A novel genetic pathway for su ...... onduction system cell lineages
@nl
prefLabel
A novel genetic pathway for su ...... onduction system cell lineages
@ast
A novel genetic pathway for su ...... onduction system cell lineages
@en
A novel genetic pathway for su ...... onduction system cell lineages
@nl
P2093
P1433
P1476
A novel genetic pathway for su ...... onduction system cell lineages
@en
P2093
A. B. Brown
G. K. Feld
K. C. Wollert
K. R. Chien
L. W. Norman
M. M. Rahme
P. Ruiz-Lozano
R. B. Clark
R. G. Gourdie
P304
P356
10.1016/S0092-8674(00)00089-1
P407
P577
2000-09-01T00:00:00Z