IgEb immune complexes activate macrophages through FcgammaRIV binding
about
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammationCritical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexesDependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice.Evidence for neuronal expression of functional Fc (epsilon and gamma) receptorsInhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRIIgE immune complexes stimulate an increase in lung mast cell progenitors in a mouse model of allergic airway inflammationFcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo.Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases.Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malariaMHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in miceInhibition of CD23-mediated IgE transcytosis suppresses the initiation and development of allergic airway inflammation.Dependence of antibody-mediated presentation of antigen on FcRnLymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV.IgE-mediated enhancement of CD4(+) T cell responses requires antigen presentation by CD8α(-) conventional dendritic cells.Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies.Deletion of activating Fcgamma receptors does not confer protection in murine cryoglobulinemia-associated membranoproliferative glomerulonephritisTargeting the neonatal fc receptor for antigen delivery using engineered fc fragments.Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays.Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells.Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10.Fc-receptors and immunity to malaria: from models to vaccines.IgE and mast cells in allergic disease.Of mice and men: the need for humanized mouse models to study human IgG activity in vivo.bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.B Cell Intrinsic Mechanisms Constraining IgE Memory.Both FcγRIV and FcγRIII are essential receptors mediating type II and type III autoimmune responsesviaFcRγ-LAT-dependent generation of C5a
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P2860
IgEb immune complexes activate macrophages through FcgammaRIV binding
description
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juli 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2007/07/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/07/01)
@nl
наукова стаття, опублікована в липні 2007
@uk
مقالة علمية (نشرت في يوليو 2007)
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name
IgEb immune complexes activate macrophages through FcgammaRIV binding
@ast
IgEb immune complexes activate macrophages through FcgammaRIV binding
@en
IgEb immune complexes activate macrophages through FcgammaRIV binding
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type
label
IgEb immune complexes activate macrophages through FcgammaRIV binding
@ast
IgEb immune complexes activate macrophages through FcgammaRIV binding
@en
IgEb immune complexes activate macrophages through FcgammaRIV binding
@nl
prefLabel
IgEb immune complexes activate macrophages through FcgammaRIV binding
@ast
IgEb immune complexes activate macrophages through FcgammaRIV binding
@en
IgEb immune complexes activate macrophages through FcgammaRIV binding
@nl
P2093
P921
P3181
P356
P1433
P1476
IgEb immune complexes activate macrophages through FcgammaRIV binding
@en
P2093
Kentaro Shimizu
Koichi Kato
Masayuki Hirano
Max D Cooper
Randall S Davis
Robert P Stephan
Shugo Nakamura
W David Fine
P304
P3181
P356
10.1038/NI1477
P407
P577
2007-06-10T00:00:00Z