Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis
about
"You Shall Not Pass"-tight junctions of the blood brain barrierAngiomotin-like proteins associate with and negatively regulate YAP1Rho GAPs and GEFs: controling switches in endothelial cell adhesionRegulation of localization and function of the transcriptional co-activator YAP by angiomotin.Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domainComparative mRNA and microRNA expression profiling of three genitourinary cancers reveals common hallmarks and cancer-specific molecular events.Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.PIV5 M protein interaction with host protein angiomotin-like 1Microenvironment, oncoantigens, and antitumor vaccination: lessons learned from BALB-neuT mice.Extracellular matrix, inflammation, and the angiogenic response.Angiomotin Family Members: Oncogenes or Tumor Suppressors?Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation.Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis.The Amotl2 gene inhibits Wnt/β-catenin signaling and regulates embryonic development in zebrafishTranscriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro.Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish.AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by MerlinApicobasal polarity of brain endothelial cells.Junctional proteins of the blood-brain barrier: New insights into function and dysfunction.Angiomotin promotes renal epithelial and carcinoma cell proliferation by retaining the nuclear YAP.Ups and downs of guided vessel sprouting: the role of polarity.Polarizing pathways: balancing endothelial polarity, permeability, and lumen formation.The Angiomotins--from discovery to function.Molecular and cellular events during blastocyst implantation in the receptive uterus: clues from mouse modelsThe E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching.Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis.AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development.AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair.A CREB-MPP7-AMOT Regulatory Axis Controls Muscle Stem Cell Expansion and Self-Renewal Competence.A missense mutation in TRAPPC6A leads to build-up of the protein, in patients with a neurodevelopmental syndrome and dysmorphic features.AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility.Hippo-YAP/TAZ Signaling in Angiogenesis.The physiological role of Motin family and its dysregulation in tumorigenesis.
P2860
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P2860
Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis
description
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juli 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/07/31)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/07/31)
@nl
наукова стаття, опублікована в липні 2009
@uk
مقالة علمية (نشرت في 31-7-2009)
@ar
name
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@ast
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@en
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@nl
type
label
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@ast
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@en
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@nl
prefLabel
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@ast
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@en
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@nl
P2093
P921
P3181
P1433
P1476
Angiomotin-like protein 1 cont ...... during sprouting angiogenesis
@en
P2093
Arindam Majumdar
Inèz Meijer
Jean-Paul Borg
Lars Holmgren
Simona Vertuani
Staffan Nyström
Stéphane Audebert
Tetyana Tegnebratt
Yujuan Zheng
P304
P3181
P356
10.1161/CIRCRESAHA.109.195156
P577
2009-07-31T00:00:00Z