Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities
about
The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysisCatalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysisExpression and biochemical characterization of the Plasmodium falciparum DNA repair enzyme, flap endonuclease-1 (PfFEN-1)Comprehensive classification of the PIN domain-like superfamilyNovel function of the flap endonuclease 1 complex in processing stalled DNA replication forksThe pathogenesis of Machado Joseph Disease: a high manganese/low magnesium initiated CAG expansion mutation in susceptible genotypes?Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ionsHigh risk of benzo[α]pyrene-induced lung cancer in E160D FEN1 mutant miceAmino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development.Endonuclease V: an unusual enzyme for repair of DNA deamination.Roles of divalent metal ions in flap endonuclease-substrate interactions.Kinetic analysis of product release and metal ions in a metallonuclease.Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease.Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substratesThree metal ions participate in the reaction catalyzed by T5 flap endonuclease.Active site substitutions delineate distinct classes of eubacterial flap endonuclease.Metal ion and DNA binding by single-chain PvuII endonuclease: lessons from the linker.
P2860
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P2860
Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/13)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/13)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في 13-8-2002)
@ar
name
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@ast
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@en
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@nl
type
label
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@ast
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@en
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@nl
prefLabel
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@ast
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@en
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@nl
P2093
P356
P1433
P1476
Distinct roles of two Mg2+ bin ...... flap endonuclease-1 activities
@en
P2093
Binghui Shen
Jixiu Shan
Ramaswamy Krishnamoorthi
P304
10323–10331
P356
10.1021/BI025841S
P407
P577
2002-08-13T00:00:00Z