Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates
about
Differential interaction kinetics of a bipolar structure-specific endonuclease with DNA flaps revealed by single-molecule imagingCellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active siteInteracting partners of FEN1 and its role in the development of anticancer therapeutics.Single-molecule FRET reveals a corkscrew RNA structure for the polymerase-bound influenza virus promoter.Polymorphism of the flap endonuclease 1 gene in keratoconus and Fuchs endothelial corneal dystrophy.Sequential switching of binding partners on PCNA during in vitro Okazaki fragment maturation.Förster resonance energy transfer and protein-induced fluorescence enhancement as synergetic multi-scale molecular rulersHigh-affinity RNA binding by a hyperthermophilic single-stranded DNA-binding proteinDistinguishing between cancer cell differentiation and resistance induced by all-trans retinoic acid using transcriptional profiles and functional pathway analysisSingle-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1.Binding dynamics of a monomeric SSB protein to DNA: a single-molecule multi-process approach.A Quantitative Theoretical Framework For Protein-Induced Fluorescence Enhancement-Förster-Type Resonance Energy Transfer (PIFE-FRET).DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction.Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.Positioning the 5'-flap junction in the active site controls the rate of flap endonuclease-1-catalyzed DNA cleavage.Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway.Effects of elemene on inhibiting proliferation of vascular smooth muscle cells and promoting reendothelialization at the stent implantation site.Characterizing highly dynamic conformational states: The transcription bubble in RNAP-promoter open complex as an example.
P2860
Q27323947-D15C0C46-5C22-4B4B-8013-446AF8D9A846Q27727694-DB5EAECB-9197-4E04-B3D1-731B20B92588Q33689135-887F09A5-75F4-4093-8B28-6BB6300224F6Q34060786-A62BF099-DDF4-4DCE-8066-5F6960250AC3Q34158710-947733AF-035A-4260-A73E-AD291C5B0BD3Q34314443-4013D013-6BD1-4BBD-964B-37AB7C267ECCQ36136743-D0217D12-162F-4683-89A3-43FFDCCF9089Q36245957-6C5879F6-5596-4252-9325-F1A8255BD392Q36972599-5B300B31-1497-49AC-8C01-BC85F3A2603AQ37712232-C2406139-8A8D-4E82-B214-6EDADBF4573FQ38295252-7A3B0262-9CC6-4FA3-9D21-9FF34A5CB650Q39762178-D4B4AD7F-5034-4B7B-A2BA-724CDEDDD9F7Q39971733-604EDFBA-6A7C-4802-8E70-D8686BDC141CQ41682746-835A9159-F667-45AD-8BCE-5584F7D61692Q49806501-05F7E242-D41B-4F48-A37B-558BD50C0AC4Q50113616-3E7C45F1-4F0A-49B3-9CBD-F086A0E40563Q50875840-5B625961-9382-46ED-A7CB-CE1934404111Q52335730-29E80547-85E3-47F4-9EAD-4432EC165C12
P2860
Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Single-molecule characterizati ...... exes acting on flap substrates
@en
type
label
Single-molecule characterizati ...... exes acting on flap substrates
@en
prefLabel
Single-molecule characterizati ...... exes acting on flap substrates
@en
P2860
P50
P356
P1476
Single-molecule characterizati ...... exes acting on flap substrates
@en
P2093
Alfonso Brenlla
Richard D Hutton
P2860
P304
P356
10.1093/NAR/GKT1116
P577
2013-11-13T00:00:00Z